Lockie P, Leong L K, Louis A
Aust N Z J Ophthalmol. 1986 Feb;14(1):49-53. doi: 10.1111/j.1442-9071.1986.tb00007.x.
A retrospective analysis of 80 cases of gonococcal ophthalmia revealed six (7.5%) to be due to penicillinase-producing Neisseria gonorrhoeae (PPNG), five neonatal cases and one adult. All six cases were finally cured, but best results were obtained with topical chloramphenicol and single-dose spectinomycin (40 mg/kg) given intramuscularly. All gonococcal isolates should be tested promptly for penicillinase production, and if this is present systemic treatment, modified to spectinomycin or penicillinase-stable cephalosporin, should be given as single-dose treatment.
对80例淋菌性眼炎的回顾性分析显示，其中6例（7.5%）由产青霉素酶的淋病奈瑟菌（PPNG）引起，包括5例新生儿病例和1例成人病例。所有6例最终均治愈，但局部使用氯霉素和肌内注射单剂量大观霉素（40mg/kg）效果最佳。所有淋病奈瑟菌分离株均应立即检测是否产青霉素酶，若产酶，则应改为使用大观霉素或对青霉素酶稳定的头孢菌素进行单剂量全身治疗。
