Department of Neurosurgery, The Third Hospital Affiliated to Soochow University, Suzhou, 215021, China.
Department of Neurosurgery, Suzhou Kowloon Hospital, Shanghai Jiaotong University School of Medicine, Suzhou, 215021, China.
Acta Neurol Belg. 2019 Sep;119(3):439-444. doi: 10.1007/s13760-019-01099-2. Epub 2019 Mar 6.
The purpose of our study was to review and evaluate the efficacy and safety of nerve combing without neurovascular decompression for trigeminal neuralgia.
A retrospective review of 298 patients with trigeminal neuralgia between August 2007 and August 2016 was conducted. The patients were divided into two groups: the A group was treated by nerve combing (34 patients) and the B group received microvascular decompression (264 patients). Surgical outcomes and postoperative complications were compared between the two groups.
Pain was completely relieved in 88.2% of group A patients and 92.8% of group B after surgery. The median duration of follow-up was 60 months (range 10-115 months) in group A and 62 months (range 12-118 months) in group B. 72.7% and 86.4% of cases were completely relieved in groups A and B, respectively. There were no statistically significant differences in the surgical outcomes between the two groups. Almost all patients experienced some degree of numbness or hypesthesia (76.5%). The rate of facial numbness in group A was significantly higher than that in group B.
This study demonstrated that nerve combing without neurovascular decompression is a safe and effective treatment for trigeminal neuralgia. However, a majority of patients treated with nerve combing experienced some degree of facial numbness.
本研究旨在回顾和评估不进行神经减压的神经梳理治疗三叉神经痛的疗效和安全性。
回顾性分析 2007 年 8 月至 2016 年 8 月期间 298 例三叉神经痛患者的临床资料。将患者分为两组：A 组行神经梳理（34 例），B 组行微血管减压术（264 例）。比较两组患者的手术效果和术后并发症。
A 组患者术后疼痛完全缓解率为 88.2%，B 组为 92.8%。A 组的中位随访时间为 60 个月（范围 10-115 个月），B 组为 62 个月（范围 12-118 个月）。A 组和 B 组分别有 72.7%和 86.4%的患者完全缓解。两组手术效果无统计学差异。几乎所有患者均出现不同程度的麻木或感觉迟钝（76.5%）。A 组患者面部麻木发生率明显高于 B 组。
本研究表明，不进行神经减压的神经梳理治疗三叉神经痛是一种安全有效的治疗方法。然而，大多数接受神经梳理治疗的患者都经历了一定程度的面部麻木。
