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Biological variations of lysozyme concentration in the tear fluids of healthy persons.健康人泪液中溶菌酶浓度的生物学变异
Br J Ophthalmol. 1986 Apr;70(4):246-8. doi: 10.1136/bjo.70.4.246.
2
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Immunoassay of tear lysozyme in acute adenovirus conjunctivitis.急性腺病毒结膜炎泪液溶菌酶的免疫测定
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5
Immunoassay of human tear lysozyme.
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6
Diurnal profiles of tear lysozyme and gamma A globulin.泪液溶菌酶和γA球蛋白的昼夜变化情况
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7
Immunochemical determination of human tear lysozyme (muramidase) in keratoconjunctivitis sicca.
Clin Chim Acta. 1982 May 20;121(2):251-60. doi: 10.1016/0009-8981(82)90066-3.
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Tear lysozyme measurements in chronic blepharitis.
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Human tear lysozyme. A comparison of electro-immunodiffusion, radial immunodiffusion and a spectrophotometric assay.
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Corneal Expression of SLURP-1 by Age, Sex, Genetic Strain, and Ocular Surface Health.不同年龄、性别、遗传品系及眼表健康状况下SLURP-1在角膜中的表达
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Tear lacritin levels by age, sex, and time of day in healthy adults.健康成年人的泪液乳铁蛋白水平按年龄、性别和时间的变化。
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本文引用的文献

1
Filter-paper electrophoresis of tears. I. Lysozyme and its correlation with keratoconjunctivitis sicca.泪液的滤纸电泳。I. 溶菌酶及其与干燥性角结膜炎的相关性。
Am J Ophthalmol. 1955 Feb;39(2 Pt 2):200-2.
2
The questionably dry eye.可疑的干眼症
Br J Ophthalmol. 1981 Jan;65(1):2-9. doi: 10.1136/bjo.65.1.2.
3
Determination of lysozyme in tears by immunoturbidimetric and optimised kinetic bacteriolytic methods.采用免疫比浊法和优化的动力学溶菌法测定泪液中的溶菌酶。
Clin Chim Acta. 1983 Apr;129(2):201-9. doi: 10.1016/0009-8981(83)90217-6.
4
Quantitation of tear lysozyme levels in dry-eye disorders.干眼症中泪液溶菌酶水平的定量分析。
Arch Ophthalmol. 1983 Apr;101(4):634-5. doi: 10.1001/archopht.1983.01040010634022.
5
Immunoassay of human tear lysozyme.
Am J Ophthalmol. 1980 Nov;90(5):715-8. doi: 10.1016/s0002-9394(14)75143-8.
6
Normal tear protein profiles and age-related changes.正常泪液蛋白质谱及与年龄相关的变化。
Br J Ophthalmol. 1984 May;68(5):316-20. doi: 10.1136/bjo.68.5.316.
7
Paralimbal ring keratitis and absence of lysozyme.角膜缘环角膜炎与溶菌酶缺乏
Am J Ophthalmol. 1965 Sep;60(3):532-5. doi: 10.1016/0002-9394(65)90726-9.
8
Human tear lysozyme. 3. Preliminary study on lysozyme levels in subjects with smog eye irritation.人泪溶菌酶。3. 对受烟雾眼刺激者溶菌酶水平的初步研究。
Am J Ophthalmol. 1968 Jul;66(1):76-80.
9
Estimation of tears lysozyme in some eye diseases.某些眼部疾病中泪液溶菌酶的测定
Bull Ophthalmol Soc Egypt. 1971;64(68):285-97.
10
Human tear lysozyme. II. Quantitative determination with standard Schirmer strips.人泪溶菌酶。II. 用标准泪液滤纸条进行定量测定。
Am J Ophthalmol. 1968 Jul;66(1):70-6.

健康人泪液中溶菌酶浓度的生物学变异

Biological variations of lysozyme concentration in the tear fluids of healthy persons.

作者信息

Sen D K, Sarin G S

出版信息

Br J Ophthalmol. 1986 Apr;70(4):246-8. doi: 10.1136/bjo.70.4.246.

DOI:10.1136/bjo.70.4.246
PMID:3083863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1040990/
Abstract

Concentration of tear lysozyme was measured in healthy Indian subjects of the same racial group aged 2 to 78 years by a single radial immunodiffusion technique. Variations in its concentration between the two eyes, during the day, over a period of time, in both sexes, and in different age groups were studied. The diurnal and age-related changes in the concentration of tear lysozyme were found to vary to an appreciable extent. The mean lysozyme concentration in tears was lower in the morning and higher in the evening. It tended to be low in children under 16, rose and attained a plateau in the age group 16-45 years and fell in later life, though still remaining higher than in the children.

摘要

采用单向放射免疫扩散技术,对年龄在2至78岁的同一种族健康印度受试者的泪液溶菌酶浓度进行了测量。研究了两眼之间、一天内、一段时间内、男女之间以及不同年龄组中其浓度的变化。发现泪液溶菌酶浓度的昼夜变化和与年龄相关的变化有相当程度的差异。泪液中溶菌酶的平均浓度早晨较低,晚上较高。16岁以下儿童的浓度往往较低,在16至45岁年龄组中上升并达到稳定水平,在晚年下降,不过仍高于儿童。