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健康人泪液中溶菌酶浓度的生物学变异

Biological variations of lysozyme concentration in the tear fluids of healthy persons.

作者信息

Sen D K, Sarin G S

出版信息

Br J Ophthalmol. 1986 Apr;70(4):246-8. doi: 10.1136/bjo.70.4.246.

Abstract

Concentration of tear lysozyme was measured in healthy Indian subjects of the same racial group aged 2 to 78 years by a single radial immunodiffusion technique. Variations in its concentration between the two eyes, during the day, over a period of time, in both sexes, and in different age groups were studied. The diurnal and age-related changes in the concentration of tear lysozyme were found to vary to an appreciable extent. The mean lysozyme concentration in tears was lower in the morning and higher in the evening. It tended to be low in children under 16, rose and attained a plateau in the age group 16-45 years and fell in later life, though still remaining higher than in the children.

摘要

采用单向放射免疫扩散技术,对年龄在2至78岁的同一种族健康印度受试者的泪液溶菌酶浓度进行了测量。研究了两眼之间、一天内、一段时间内、男女之间以及不同年龄组中其浓度的变化。发现泪液溶菌酶浓度的昼夜变化和与年龄相关的变化有相当程度的差异。泪液中溶菌酶的平均浓度早晨较低,晚上较高。16岁以下儿童的浓度往往较低,在16至45岁年龄组中上升并达到稳定水平,在晚年下降,不过仍高于儿童。

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