感觉反应过度参与者的静息态脑电图：一项探索性研究。
Resting-State Electroencephalography in Participants With Sensory Overresponsiveness: An Exploratory Study.
作者信息
Granovsky Yelena, Weissman-Fogel Irit, Bar-Shalita Tami
机构信息
Yelena Granovsky, PhD, is Senior Lecturer, Rambam Health Care Campus, Haifa, Israel, and Technion Medical Faculty, Haifa, Israel.
Irit Weissman-Fogel, PhD, is Senior Lecturer, University of Haifa, Haifa, Israel.
出版信息
Am J Occup Ther. 2019 Jan/Feb;73(1):7301205100p1-7301205100p11. doi: 10.5014/ajot.2019.029231.
OBJECTIVE
People with sensory overresponsiveness (SOR) perceive nonpainful stimuli as noxious and demonstrate hyperalgesia and lingering sensation to laboratory pain stimuli. Electroencephalography (EEG) of cortical activity at rest is widely used to explore endophenotypes but has not yet been tested in people with SOR. Therefore, we investigated the characteristics of resting-state EEG in participants with SOR.
METHOD
Resting-state EEG (5-min, eyes-closed recording) was compared in participants with (n = 9) and without (n = 12) SOR.
RESULTS
Participants with SOR demonstrated a global reduction of the EEG activity, including significantly lower θ and α1 activity as well as faster peak α frequency. Higher sensory-responsiveness scores were associated with high peak α power in participants without SOR.
CONCLUSION
Reduced α activity is commonly interpreted as an electrophysiological indicator of arousal and sensitivity to pain. The EEG pattern of response may partly explain the reported ongoing daily alertness to environmental stimuli in participants with SOR.
目的
感觉反应过度（SOR）的人会将非疼痛性刺激视为有害刺激，并对实验室疼痛刺激表现出痛觉过敏和持续感觉。静息状态下的皮质活动脑电图（EEG）被广泛用于探索内表型，但尚未在SOR患者中进行测试。因此，我们研究了SOR参与者静息态脑电图的特征。
方法
对有SOR（n = 9）和无SOR（n = 12）的参与者的静息态脑电图（闭眼记录5分钟）进行比较。
结果
SOR参与者表现出脑电图活动整体降低，包括显著更低的θ和α1活动以及更快的α峰值频率。在无SOR的参与者中，更高的感觉反应评分与高α峰值功率相关。
结论
α活动降低通常被解释为唤醒和对疼痛敏感性的电生理指标。脑电图反应模式可能部分解释了报告中SOR参与者对环境刺激持续的日常警觉性。
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