Sacks S H, Hall I, Ragge N, Pritchard J
Br Med J (Clin Res Ed). 1986 Apr 26;292(6528):1097-8. doi: 10.1136/bmj.292.6528.1097.
Two young patients presented with generalised lymphadenopathy, otorrhoea, otitis, and rash. Over the next few years chronically discharging sinuses began to form over enlarged nodes and histological appearances were typical of histiocytosis X. In neither case were micro-organisms isolated from the lesions, and in both patients healing occurred with immunosuppressive agents. Chronic dermal sinus formation secondary to lymph node disease has never before been recorded as a manifestation of histiocytosis X. Histiocytosis X should therefore be considered in the differential diagnosis of "suppurative" lymphadenopathy so that appropriate treatment may be given without delay.
两名年轻患者出现全身淋巴结肿大、耳漏、中耳炎及皮疹。在接下来的几年里，肿大淋巴结上开始形成慢性排脓窦道，组织学表现为典型的组织细胞增多症X。两例病变均未分离出微生物，两名患者经免疫抑制剂治疗后均痊愈。淋巴结疾病继发慢性皮肤窦道形成此前从未被记录为组织细胞增多症X的一种表现。因此，在“化脓性”淋巴结病的鉴别诊断中应考虑组织细胞增多症X，以便及时给予适当治疗。
