Division of Transplant Surgery, Department of Surgery, Virginia Commonwealth University, PO Box 980057, Richmond, VA, 23298-0057, USA.
Division of Transplantation and Hepatobiliary Surgery, University of Florida, Gainesville, FL, USA.
Dig Dis Sci. 2019 Apr;64(4):976-984. doi: 10.1007/s10620-019-05550-5.
Liver transplantation is the definitive treatment for patients with end-stage liver disease. Liver transplantation is also the optimal treatment for patients with hepatocellular carcinoma (HCC), especially in the setting of chronic liver disease. Unfortunately, due to the worldwide shortage of organs, this treatment is not available for all patients with HCC. Strict selection criteria have been developed in order to obtain optimal results. A surgical perspective of the preoperative selection, perioperative management, and postoperative care of patients is reviewed in depth and provides an overview for obtaining optimal long-term results from liver transplantation for HCC. With rigorous selection and patient management, excellent long-term outcomes can be obtained with liver transplantation for patients with HCC.
肝移植是终末期肝病患者的确定性治疗方法。肝移植也是肝细胞癌(HCC)患者的最佳治疗方法,尤其是在慢性肝病的情况下。不幸的是,由于全球器官短缺,并非所有 HCC 患者都能接受这种治疗。为了获得最佳结果,已经制定了严格的选择标准。本文深入回顾了肝移植治疗 HCC 患者的术前选择、围手术期管理和术后护理的手术观点,并提供了获得肝移植 HCC 最佳长期结果的概述。通过严格的选择和患者管理,可以为 HCC 患者进行肝移植获得极好的长期结果。