Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
Korean J Intern Med. 2019 Mar;34(2):261-268. doi: 10.3904/kjim.2019.044. Epub 2019 Feb 25.
The most effective and fundamental treatment for end-stage liver disease is liver transplantation. Deceased-donor liver transplantation has been performed for many of these cases. However, living-donor liver transplantation (LDLT) has emerged as an alternative because it enables timely procurement of the donor organ. The success rate of LDLT has been improved by development of the surgical technique, use of immunosuppressant drugs, and accumulation of post-transplantation care experience. However, the occurrence of biliary stricture after LDLT remains a problem. This article reviews the pathogenesis, diagnosis, endoscopic management, and long-term outcomes of post-liver transplantation biliary stricture, with a focus on anastomotic stricture.
对于终末期肝病，最有效和最根本的治疗方法是肝移植。对于许多这样的病例，已经进行了已故供体肝移植。然而，活体供体肝移植（LDLT）已成为一种替代方法，因为它可以及时获得供体器官。通过发展手术技术、使用免疫抑制剂药物和积累移植后护理经验，LDLT 的成功率得到了提高。然而，LDLT 后胆管狭窄的发生仍然是一个问题。本文综述了肝移植后胆管狭窄的发病机制、诊断、内镜治疗和长期预后，重点介绍吻合口狭窄。
