Kamus Louis, Rameau Marie, Theoret Christine
Département de biomédecine vétérinaire, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, QC, J2S 2M2, Canada.
BMC Vet Res. 2019 Mar 6;15(1):78. doi: 10.1186/s12917-019-1829-5.
Wounds are among the most common medical conditions affecting horses and have a major economic impact on the horse industry. Wound healing in horses is distinct to that documented in other species, and often results in delayed healing and extensive scarring, with compromised functional and aesthetic outcomes. To date, there is no conventional method objectively proven to accelerate healing or to successfully prevent complications associated with second intention healing. Several effects of Negative Pressure Wound Therapy (NPWT) may be particularly useful to the management of wounds in horses. However, cumbersome designs of classic NPWT devices render them unsuitable for equine practice. A new lightweight, portable and disposable unit of NPWT (PICO®), should facilitate the use of this modality by equine practitioners. The aim of this study was to evaluate the feasibility of using this canister-free system to treat experimental open wounds in horses.
No difficulties were encountered with the application or maintenance of the PICO® system during the ex vivo experiment or during the preliminary in vivo experiment conducted on intact skin. All horses readily tolerated the PICO® but difficulties with adhesion and seal prevented the completion of the experimental wound study despite the use of many adjunctive adhesives.
The current PICO® dressing design is not suitable to be used as a dressing for open wounds in horses though the device is well tolerated by equine patients. A dressing with a wider adhesive edge, a superior adhesive and a more flexible pad would likely be better adapted to enable its future use in equine practice.
伤口是影响马匹的最常见病症之一，对养马业有重大经济影响。马匹的伤口愈合与其他物种记录的情况不同，常导致愈合延迟和广泛瘢痕形成，功能和美观效果受损。迄今为止，尚无经客观证实的常规方法可加速愈合或成功预防与二期愈合相关的并发症。负压伤口治疗（NPWT）的几种作用可能对马匹伤口的处理特别有用。然而，经典NPWT装置设计笨重，不适合用于马匹治疗。一种新型轻便、便携且一次性使用的NPWT装置（PICO®），应便于马匹从业者使用这种治疗方式。本研究的目的是评估使用这种无罐系统治疗马匹实验性开放性伤口的可行性。
在体外实验或在完整皮肤上进行的初步体内实验期间，PICO®系统的应用或维护均未遇到困难。所有马匹都能很好地耐受PICO®，但尽管使用了多种辅助粘合剂，粘连和密封问题仍导致实验性伤口研究无法完成。
尽管马匹患者对PICO®装置耐受性良好，但目前的PICO®敷料设计不适合用作马匹开放性伤口的敷料。具有更宽粘合边缘、更好粘合剂和更灵活衬垫的敷料可能更适合，以便未来能在马匹治疗中使用。
