Nolff M C, Fehr M, Bolling A, Dening R, Kramer S, Reese S, Meyer-Lindenberg A
Dr. Mirja Christine Nolff, Ludwig-Maximilians-University, Clinic for Small Animal Surgery and Reproduction, Veterinärstrasse 13, 80539 Munich, Germany, E-mail:
Vet Comp Orthop Traumatol. 2015;28(1):30-8. doi: 10.3415/VCOT-14-05-0076. Epub 2014 Dec 2.
To evaluate negative pressure wound therapy (NPWT) for treatment of complicated wounds in dogs.
Retrospective multicentre study.
Dogs (n = 50) undergoing open wound treatment were classified according to treatment method used: bandage (Group A, n = 7), NPWT (Group B, n = 18), and foam dressing (Group C, n = 25). Pairs of patients matched based on wound conformation, localization, and underlying cause were compared between Group A and C (n = 7 pairs) and between groups B and C (n = 18 pairs) in terms of duration of previous treatment, time to closure, and complications.
Signalment, antibiotic medications, antiseptic treatment, and bacterial status of wounds were comparable between groups. The duration of previous treatment was significantly higher in patients assigned to Group B (p = 0.04) compared to Group C, while no significant difference was found between groups A and B. Total time to wound closure was significantly shorter in Group C compared to Group A (p = 0.02) and in Group B compared to Group C (p = 0.003). Wounds treated with NPWT suffered significantly less complications (p = 0.008) and were significantly less septic during treatment (p = 0.016) than wounds treated with a foam dressing.
This study shows that time to healing was halved in NPWT treated patients compared to foam dressing treated patients, which in turn healed faster than patients treated with conventional bandage, underlining the value of NPWT therapy for the treatment of complicated wounds.
评估负压伤口治疗(NPWT)对犬类复杂伤口的治疗效果。
回顾性多中心研究。
对接受开放性伤口治疗的犬只(n = 50)根据所采用的治疗方法进行分类:绷带治疗(A组,n = 7)、NPWT治疗(B组,n = 18)和泡沫敷料治疗(C组,n = 25)。在伤口形态、位置和潜在病因相匹配的成对患者中,比较A组和C组(n = 7对)以及B组和C组(n = 18对)在先前治疗持续时间、伤口闭合时间和并发症方面的情况。
各组之间的信号、抗生素用药、防腐处理和伤口细菌状况具有可比性。与C组相比,B组患者的先前治疗持续时间显著更长(p = 0.04),而A组和B组之间未发现显著差异。与A组相比,C组的伤口总闭合时间显著更短(p = 0.02),与C组相比,B组的伤口总闭合时间也显著更短(p = 0.003)。与使用泡沫敷料治疗的伤口相比,接受NPWT治疗的伤口并发症显著更少(p = 0.008),且治疗期间感染性显著更低(p = 0.016)。
本研究表明,与使用泡沫敷料治疗的患者相比,接受NPWT治疗的患者愈合时间减半,而使用泡沫敷料治疗的患者又比接受传统绷带治疗的患者愈合得更快,这突出了NPWT疗法在治疗复杂伤口方面的价值。