Chu Lisa, Howell Brooke, Steinberg Alissa, Bar-Dayan Alisa, Toulany Alene, Langer Jacob C, Hamilton Jill K
SickKids Team Obesity Management Program, Division of Endocrinology, The Hospital for Sick Children, Toronto, Canada.
Department of Paediatrics, University of Toronto, Toronto, Canada.
Pediatr Obes. 2019 Aug;14(8):e12519. doi: 10.1111/ijpo.12519. Epub 2019 Mar 6.
Growing evidence supports the efficacy of paediatric bariatric surgery. However, there is a paucity of data examining adolescent outcomes post surgery. Among adults, studies have shown that early weight loss is associated with long-term weight loss. Therefore, the aim of our study was to investigate the association between early weight loss at 3 months with longer-term weight loss at 12 and 24 months in adolescents post surgery. We hypothesized that patients who have greater weight loss within the first 3 months will have greater weight loss at 12 and 24 months post surgery.
A retrospective chart review of bariatric surgery patients (n = 28) was conducted. Anthropometric measurements at baseline and 3, 12, and 24 months were analysed.
Percent of excess weight loss (%EWL) at 3, 12, and 24 months were 33.6 ± 11.3%, 55.0 ± 20.5%, and 55.1 ± 27.1%, respectively. %EWL at 3 months was positively associated with %EWL at 12 and 24 months (P < 0.05). Receiver operating characteristic curve results identified a cut-off of greater than or equal to 30%EWL at 3 months predicted successful weight loss, defined as greater than or equal to 50%EWL at 12 and 24 months.
These findings demonstrate that majority of weight loss among adolescents occurs within the first postoperative year. Greater %EWL by 3 months post surgery predicts successful and sustained weight loss over time.
越来越多的证据支持小儿减肥手术的疗效。然而，关于术后青少年预后的数据却很少。在成年人中，研究表明早期体重减轻与长期体重减轻有关。因此，我们研究的目的是调查青少年术后3个月时的早期体重减轻与12个月和24个月时的长期体重减轻之间的关联。我们假设在术后前3个月体重减轻更多的患者在术后12个月和24个月时体重减轻也更多。
对减肥手术患者（n = 28）进行回顾性病历审查。分析了基线时以及术后3个月、12个月和24个月时的人体测量数据。
术后3个月、12个月和24个月时的超重减轻百分比（%EWL）分别为33.6 ± 11.3%、55.0 ± 20.5%和55.1 ± 27.1%。术后3个月时的%EWL与术后12个月和24个月时的%EWL呈正相关（P < 0.05）。受试者工作特征曲线结果确定，术后3个月时%EWL大于或等于30%可预测减肥成功，减肥成功定义为术后12个月和24个月时%EWL大于或等于50%。
这些发现表明，青少年的大部分体重减轻发生在术后第一年。术后3个月时较高的%EWL可预测随着时间推移减肥成功且体重持续减轻。
