Department of Otology and Skull Base Surgery, Eye and ENT Hospital, Fudan University, Shanghai, China; NHC Key Laboratory of Hearing Medicine, Fudan University, Shanghai, China.
Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.
World Neurosurg. 2019 Jun;126:e688-e693. doi: 10.1016/j.wneu.2019.02.124. Epub 2019 Mar 4.
Neurorrhaphy with interpositional graft is a practical technique to achieve facial reanimation when the continuity of the facial nerve is interrupted and a large gap between the proximal and distal stump exists. The aim of this study was to report long-term outcomes of neurorrhaphy for facial reanimation with interpositional graft. The roles of some variable factors in the outcome of neurorrhaphy with interpositional graft were also evaluated and compared.
A retrospective case series from a single tertiary referral center comprised 23 patients with facial nerve interruptions who underwent neurorrhaphy with interpositional graft using either end-to-end anastomosis or end-to-side hypoglossal-facial technique. Preoperative data (age, sex, primary lesion, interval from paralysis to surgery, facial nerve function), intraoperative data (surgical approach, graft and type of neurorrhaphy), and postoperative data (facial nerve function) were collected and analyzed.
Mean follow-up time was 26.6 ± 11.9 months. Patients who underwent neurorrhaphy for facial reanimation within 1 year after onset of facial paralysis were more likely to achieve House-Brackmann grade ≤3 compared with patients who underwent neurorrhaphy >1 year after onset of facial paralysis (odds ratio = 23.85, P = 0.04). No other factors were associated with improved outcomes.
Early neurorrhaphy with interpositional graft (≤1 year) for facial reanimation resulted in better final facial nerve function outcomes compared with a delayed procedure.
神经吻合加移植是一种实用的技术,可以在面神经中断且近端和远端残端之间存在较大间隙时实现面部再运动。本研究旨在报告神经吻合加移植用于面部再运动的长期结果。还评估和比较了一些可变因素在神经吻合加移植中的作用。
一项来自单一三级转诊中心的回顾性病例系列研究,包括 23 例因面神经中断而行神经吻合加移植术的患者,采用端端吻合或舌下-面神经端侧技术。收集并分析了术前数据(年龄、性别、原发性病变、从麻痹到手术的时间间隔、面神经功能)、术中数据(手术入路、移植物和神经吻合类型)和术后数据(面神经功能)。
平均随访时间为 26.6±11.9 个月。与面神经麻痹发病 1 年后行神经吻合术的患者相比,发病 1 年内行神经吻合术的患者更有可能达到 House-Brackmann 分级≤3(优势比=23.85,P=0.04)。其他因素与改善结果无关。
与延迟手术相比,早期(≤1 年)神经吻合加移植术(神经吻合加移植术)用于面部再运动可获得更好的最终面神经功能结果。