Department of Radiology, Affiliated Hospital, Jiangnan University, No. 200, Huihe Road, Wuxi, 214062, Jiangsu, China.
Department of Radiology, Affiliated Renmin Hospital, Jiangsu University, No. 8, Dianli Road, Zhenjiang, 212002, Jiangsu, China.
Cancer Imaging. 2019 Mar 7;19(1):13. doi: 10.1186/s40644-019-0198-4.
To delineate the features of multi-detector computed tomography (MDCT) images and clinical characteristics of pancreatic solid pseudopapillary tumors (SPTs) of the pancreas in asymptomatic patients and compare these features and characteristics between asymptomatic and symptomatic patients.
This work is a retrospective study approved by our institutional review board. MDCT images and clinical data of 109 patients with pathologically proven SPTs obtained from October 2008 to October 2016 were reviewed. Patients were categorized into two groups: asymptomatic patients and patients with symptomatic disease. Cases were reviewed to determine the reason for detection, intervention, shape, diameter, location, calcification, encapsulation, internal composition, CT attenuation, enhancement pattern, and tumor pathology. Clinical factors and imaging features were also compared between groups. Statistical analysis was performed using χ2 and t-tests.
Data from 49 asymptomatic and 60 symptomatic patients were collected. Asymptomatic SPTs were identified most frequently during routine health examination (18 patients, 36.7%), various screening purposes (12 patients, 24.5%), and traumatic injury (9 patients, 18.4%). Except for a smaller tumor size (5.8 cm in asymptomatic SPTs vs. 7.4 cm in symptomatic SPTs, P = 0.023), the clinical factors or imaging features of asymptomatic patients were very similar to those of symptomatic patients.
The current research is the first single-center study to characterize SPTs in asymptomatic patients. Asymptomatic SPTs are gradually being identified with greater frequency. Although generally smaller in size than that in symptomatic patients, an asymptomatic pancreatic mass with the typical imaging features of SPT may be found, the treatment for which is similar to that for symptomatic patients. Evaluating asymptomatic SPTs requires further systematic and multi-center trials.
描绘无症状患者胰腺实性假乳头状瘤（SPT）的多排螺旋 CT（MDCT）图像特征和临床特征，并比较这些特征和无症状与有症状患者之间的特征。
这是一项经我们机构审查委员会批准的回顾性研究。回顾了 2008 年 10 月至 2016 年 10 月期间，经病理证实的 109 例胰腺 SPT 患者的 MDCT 图像和临床资料。将患者分为两组：无症状患者和有症状疾病患者。对病例进行评估，以确定检测、干预、形状、直径、位置、钙化、包膜、内部成分、CT 衰减、增强模式和肿瘤病理学的原因。还比较了组间的临床因素和影像学特征。使用 χ2 和 t 检验进行统计分析。
共收集了 49 例无症状和 60 例有症状患者的数据。无症状 SPT 最常在常规健康检查（18 例，36.7%）、各种筛查目的（12 例，24.5%）和创伤性损伤（9 例，18.4%）中发现。除肿瘤较小（无症状 SPT 为 5.8cm，有症状 SPT 为 7.4cm，P=0.023）外，无症状患者的临床因素或影像学特征与有症状患者非常相似。
本研究是第一项描述无症状患者 SPT 的单中心研究。无症状 SPT 的发现频率逐渐增加。虽然无症状患者的肿瘤一般较小，但可能会发现具有 SPT 典型影像学特征的无症状胰腺肿块，其治疗与有症状患者相似。评估无症状 SPT 需要进一步的系统和多中心试验。
