伴有破骨细胞样巨细胞的低分化皮肤鳞状细胞癌：一种罕见的侵袭性变体。
Poorly differentiated cutaneous squamous cell carcinoma with osteoclast-like giant cell: A rare, aggressive variant.
作者信息
Venning Victoria L, Myint Esther, Pyne John, Clark Simon
机构信息
The Skin Hospital Sydney New South Wales Australia.
Anatomical Pathology Douglass Hanly Moir Pathology Sydney New South Wales Australia.
出版信息
Clin Case Rep. 2019 Jan 9;7(2):340-342. doi: 10.1002/ccr3.1955. eCollection 2019 Feb.
Squamous Cell Carcinoma (SCC) with Osteoclast-like giant cell (OLGC) is a rare SCC variant; only 10 cases have been reported. Our case suggests OLGC are resultant of a reactive process, driven by the fusion of adjacent macrophages. Knowledge regarding SCC with OLGC is of great importance as this entity has greater prometastatic potential compared to conventional SCC.
伴有破骨细胞样巨细胞（OLGC）的鳞状细胞癌（SCC）是一种罕见的SCC变体；仅报道过10例。我们的病例表明OLGC是由相邻巨噬细胞融合驱动的反应性过程的结果。了解伴有OLGC的SCC非常重要，因为与传统SCC相比，该实体具有更大的转移潜能。
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