Kim Min Bum, Lim Gil Chai, Park Jin A, Kim Yoo Suk, Kim Jeong Hong, Kang Ju Wan
Department of Otorhinolaryngology, Jeju National University School of Medicine, 102 Jejudaehakno, Jeju 63243, Jeju, South Korea.
Department of Otolaryngology, Ajou University School of Medicine, Suwon, South Korea.
Open Med (Wars). 2019 Feb 26;14:241-246. doi: 10.1515/med-2019-0018. eCollection 2019.
Samter's Triad is a disorder characterized by chronic rhinosinusitis (CRS) with nasal polyps (NPs), asthma, and intolerance to cyclooxygenase-1 inhibitors. However, there have been no studies investigating the prediction of Samter's Triad using imaging findings. Therefore, the authors aimed to investigate whether there is a difference in computed tomography (CT) findings between patients who have CRS with NPs and those with Samter's Triad. Patients were classified into a CRS group and a Samter group. Opacification was measured using data from CT scans by scoring each sinus on a numerical rating scale ranging from 0 to 4. The opacification scores of the ethmoid and frontal sinuses were significantly higher in the Samter's Triad group. Furthermore, Samter's Triad was more common in patients who scored ≤ 2 for maxillary opacification (7/16) than in those who scored ≥3 (4/45, p=0.005). Patients with Samter's Triad exhibited a tendency toward higher opacification scores for the ethmoid and frontal sinuses, with a relatively lower opacification score for the maxillary sinus. These findings could be helpful in distinguishing patients with Samter's Triad from those who have CRS with NPs, and to plan treatment strategies without having to perform additional laboratory or radiological tests.
Samter三联征是一种以伴有鼻息肉（NP）的慢性鼻-鼻窦炎（CRS）、哮喘以及对环氧化酶-1抑制剂不耐受为特征的疾病。然而，尚无研究利用影像学检查结果来预测Samter三联征。因此，作者旨在研究伴有NP的CRS患者与Samter三联征患者的计算机断层扫描（CT）结果是否存在差异。患者被分为CRS组和Samter组。通过使用CT扫描数据，采用0至4的数字评分量表对每个鼻窦进行评分来测量鼻窦浑浊程度。Samter三联征组筛窦和额窦的浑浊度评分显著更高。此外，上颌窦浑浊度评分为≤2分的患者中Samter三联征更为常见（7/16），高于评分≥3分的患者（4/45，p = 0.005）。Samter三联征患者筛窦和额窦的浑浊度评分有升高趋势，而上颌窦的浑浊度评分相对较低。这些发现有助于区分Samter三联征患者与伴有NP的CRS患者，并且无需进行额外的实验室或放射学检查即可制定治疗策略。
