Zhu Wei, Haga Takeshi, Yuan Dongfang, Watanabe Ken-Ichi, Chambers James K, Gao Nannan, Uchida Kazuyuki, Fan Shushan, Li Fang, Yang Mingcai, Norimine Junzo, Hu Shilin, Dong Jianbao
Department of Veterinary Medical Science, Shandong Vocational Animal Science and Veterinary College, Weifang, 261061, China.
Qinghai University and Tsinghua University Three Rivers Source Research Institute, Qinghai University, Xining, 810016, China.
Arch Virol. 2019 May;164(5):1441-1444. doi: 10.1007/s00705-019-04199-9. Epub 2019 Mar 7.
To date, there have been no reports of coinfection with bovine papular stomatitis virus (BPSV) and bovine papillomavirus (BPV) in the same lesion. In the present study, one lingual papilloma-like sample was collected at an abattoir from the tongue of a 31-month-old Japanese black cow. Coinfection with BPSV and BPV was confirmed by histopathology, immunohistochemistry, PCR and RT-PCR. The evidence for coinfection with BPSV and BPV in the same lesion and an association of BPV with lingual papillomatosis will contribute to future epidemiological studies of these two viruses.
迄今为止，尚无在同一病变中同时感染牛丘疹性口炎病毒（BPSV）和牛乳头瘤病毒（BPV）的报告。在本研究中，在一家屠宰场从一头31月龄日本黑牛的舌头采集了一个舌乳头状瘤样样本。通过组织病理学、免疫组织化学、PCR和RT-PCR证实了BPSV和BPV的共同感染。同一病变中BPSV和BPV共同感染的证据以及BPV与舌乳头状瘤病的关联将有助于这两种病毒未来的流行病学研究。
