服用奥美沙坦的患者出现显著体重减轻：一例罕见病例报告。
Significant Weight Loss in a Patient Taking Olmesartan: An Unusual Case Report.
作者信息
Makri Andromachi, Florentin Matilda, Elisaf Moses S, Liamis George
机构信息
Department of Internal Medicine, School of Medicine, University of Ioannina, Ioannina, Greece.
出版信息
Curr Drug Saf. 2019;14(3):238-241. doi: 10.2174/1574886314666190307142111.
OBJECTIVE
Olmesartan-induced enteropathy consists a syndrome that mimics celiac disease both clinically and histologically. Cases of this entity have sporadically been reported since 2012 and are usually characterized by severe diarrhea and malabsorption, followed by significant weight loss.
CASE REPORT
Herein, we report an uncommon case of this syndrome, where weight loss preceded several months the onset of gastrointestinal symptoms.
DISCUSSION AND CONCLUSION
Physicians should be aware of unexplained weight loss in patients taking olmesartan, as prompt discontinuation of the drug may prevent the deleterious consequences of malabsorption.
目的
奥美沙坦诱发的肠病是一种在临床和组织学上都类似于乳糜泻的综合征。自2012年以来，偶尔有该病症的病例报告，其通常的特征是严重腹泻和吸收不良，随后体重显著减轻。
病例报告
在此，我们报告该综合征的一例罕见病例，体重减轻发生在胃肠道症状出现前几个月。
讨论与结论
医生应意识到服用奥美沙坦的患者出现不明原因的体重减轻，因为及时停药可能会预防吸收不良的有害后果。
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