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[三例病因罕见且治疗简单的严重慢性腹泻病例]

[Three cases of severe chronic diarrhea with a rare cause and a simple therapy].

作者信息

Rommel K-P, Schneider E, Witschel I, Halm U, Zachäus M

机构信息

Universitätsklinik für Kardiologie - HELIOS Stiftungsprofessur, Herzzentrum Leipzig, Strümpellstr. 39, 04289, Leipzig, Deutschland.

Praxis für Pathologie Dres. Schneider/Schmidt, Leipzig, Deutschland.

出版信息

Internist (Berl). 2018 Sep;59(9):961-966. doi: 10.1007/s00108-018-0417-2.

Abstract

We report three cases of severe olmesartan-associated chronic diarrhea with weight loss and malassimilation syndrome. Histologically, a sprue-like enteropathy was diagnosed in each case, while serological tests for celiac disease were negative. After stopping the medication, symptoms improved within a few days. Histologically, remission was documented after 3 months. Olmesartan-associated enteropathy is an underestimated entity and an important differential diagnosis in patients with chronic diarrhea.

摘要

我们报告了三例与奥美沙坦相关的严重慢性腹泻病例,伴有体重减轻和吸收不良综合征。组织学检查显示,每例均诊断为口炎性腹泻样小肠病,而乳糜泻的血清学检测为阴性。停药后,症状在数天内改善。组织学检查显示,3个月后病情缓解。奥美沙坦相关小肠病是一个被低估的疾病实体,是慢性腹泻患者重要的鉴别诊断。

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