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胸骨伤口感染、危险因素和处理 - 我们进展到哪一步了?文献回顾。

Sternal Wound Infections, Risk Factors and Management - How Far Are We? A Literature Review.

机构信息

Department of Molecular & Clinical Medicine, Ninewells Hospital and Medical School, Dundee, UK.

Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.

出版信息

Heart Lung Circ. 2019 Jun;28(6):835-843. doi: 10.1016/j.hlc.2019.01.008. Epub 2019 Feb 2.

Abstract

Sternal wound infection (SWI) is one of the potential complications post cardiac surgery, and despite refined surgical techniques such as smaller incisions, antibiotic therapy, and optimised glycaemic control, the incidence rate is between <1% in elective cases with low risk factors and as high as 25% in patients with extensive risk factors. The presence of SWI will increase the perioperative morbidity and mortality rates and prolong the patient's hospital stay, therefore the prevention and diagnosis with appropriate management of such adverse outcomes at an early stage is important to prevent further progression as it can be fatal when the mediastinal structures are affected. Currently, the diagnosis typically consists of three main stages: clinical, biochemical including microbiology studies and imaging studies. In the current health care system, the use of computed tomography (CT) and magnetic resonance imaging (MRI) is valuable to define mediastinal abnormalities and can also help find the source of a descending infection. Management is through methods such as antibiotic therapy, surgical debridement, reconstruction with soft tissue flap coverage, sternal plating, and sternectomy. In this literature review, we aim to summarise current literature evidence behind appropriately diagnosing such a catastrophe.

摘要

胸骨伤口感染(SWI)是心脏手术后的潜在并发症之一,尽管采用了精细的手术技术,如小切口、抗生素治疗和优化血糖控制,但在低风险因素的择期病例中,发病率在<1%之间,而在广泛风险因素的患者中,发病率高达 25%。SWI 的存在会增加围手术期发病率和死亡率,并延长患者的住院时间,因此,早期预防和诊断以及适当处理此类不良后果对于防止进一步进展很重要,因为当纵隔结构受到影响时,它可能是致命的。目前,诊断通常包括三个主要阶段:临床、生化包括微生物学研究和影像学研究。在当前的医疗保健系统中,使用计算机断层扫描(CT)和磁共振成像(MRI)对于定义纵隔异常很有价值,并且还可以帮助找到下行感染的来源。治疗方法包括抗生素治疗、清创术、软组织瓣覆盖重建、胸骨板和胸骨切除术。在本次文献综述中,我们旨在总结目前关于适当诊断这种灾难的文献证据。

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