Scocca J J, Habersat M
J Bacteriol. 1978 Sep;135(3):961-7. doi: 10.1128/jb.135.3.961-967.1978.
When competent Haemophilus influenzae were returned to complete growth medium, they resumed growth at once and underwent a synchronous division after 20 to 25 min. The rate of DNA synthesis increased to the definitive rate very quickly after resumption of growth. In contrast, the rate of RNA synthesis remained low until the time of division, at which time it accelerated dramatically. Changes in the rate of protein synthesis were similar in form to those of RNA synthesis. The kinetics of loss of competence upon resumption of growth had a pattern similar to the rate of RNA synthesis, and both processes accelerated markedly at the time of cell division, suggesting an inverse relationship between RNA synthesis and the ability to take up DNA.
当有感受态的流感嗜血杆菌重新置于完全生长培养基中时，它们立即恢复生长，并在20至25分钟后进行同步分裂。恢复生长后，DNA合成速率很快增加到最终速率。相比之下，RNA合成速率在分裂前一直保持较低水平，直到分裂时才急剧加速。蛋白质合成速率的变化形式与RNA合成相似。恢复生长后感受态丧失的动力学模式与RNA合成速率相似，并且这两个过程在细胞分裂时都显著加速，这表明RNA合成与摄取DNA的能力之间存在反比关系。
