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免疫功能正常患者中变应性真菌性鼻窦炎发展为慢性侵袭性真菌性鼻窦炎。

Conversion to Chronic Invasive Fungal Sinusitis From Allergic Fungal Sinusitis in Immunocompetence.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Augusta University, Augusta, Georgia.

UMass Memorial Healthcare, Worchester, Massachusetts, U.S.A.

出版信息

Laryngoscope. 2019 Nov;129(11):2447-2450. doi: 10.1002/lary.27884. Epub 2019 Mar 9.

Abstract

A review of the treatment of allergic and invasive fungal sinusitis, as well as a presentation of the first recorded case of a conversion from allergic fungal sinusitis (AFS) to chronic granulomatous invasive sinusitis and the fourth case of invasive fungal sinusitis associated with Curvularia. This immunocompetent patient suffering from chronic AFS converted after repeated high-dose steroid tapers and noncompliance. AFS may present atypically and should be suspected even in immunocompetent patients with sinus disease who report new onset pain and neurologic symptoms. Clinicians should consider the potential complications associated with repeated systemic steroid administration. Laryngoscope, 129:2447-2450, 2019.

摘要

变应性和侵袭性真菌性鼻窦炎的治疗综述,以及首例变应性真菌性鼻窦炎(AFS)转为慢性粒细胞性侵袭性鼻窦炎病例的介绍,以及第四例与弯孢霉菌相关的侵袭性真菌性鼻窦炎。该免疫功能正常的患者患有慢性 AFS,在反复大剂量类固醇减量和不遵医嘱后发生转化。AFS 可能表现不典型,因此即使在免疫功能正常的鼻窦疾病患者中,报告新发疼痛和神经症状,也应怀疑 AFS。临床医生应考虑与反复全身类固醇给药相关的潜在并发症。《喉镜》,129:2447-2450,2019。

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