Moorman A F, de Boer P A, Lamers W H, Charles R
Acta Histochem Suppl. 1986;32:105-9.
The cellular distribution of histone H5 in embryonic and adult tissues of Xenopus laevis and chicken has been established with monoclonal antibodies to histone H5. Both in Xenopus and in chicken, the protein has presumably a more widespread cellular distribution than hitherto expected but is absent in most embryonic tissues. At least in Xenopus its presence seems not to be restricted to amitotic cells. Arguments will be put forward histone H5 in these animals should be considered as a H1(0) type of histone and that analogous to mammalian H1 degree this protein plays a role in differentiation.
利用针对组蛋白H5的单克隆抗体,已确定了非洲爪蟾和鸡的胚胎及成体组织中组蛋白H5的细胞分布。在非洲爪蟾和鸡中,该蛋白的细胞分布可能比迄今预期的更为广泛,但在大多数胚胎组织中不存在。至少在非洲爪蟾中,其存在似乎并不局限于无丝分裂细胞。将提出论据表明,这些动物中的组蛋白H5应被视为一种H1(0)型组蛋白,并且类似于哺乳动物的H1程度,这种蛋白在分化中发挥作用。