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超声引导竖脊肌平面阻滞与肋缘下斜腹横肌平面阻滞用于腹腔镜胆囊切除术成年患者术后镇痛的随机对照试验。

Ultrasound-guided erector spinae plane block versus oblique subcostal transversus abdominis plane block for postoperative analgesia of adult patients undergoing laparoscopic cholecystectomy: Randomized, controlled trial.

机构信息

Muğla Sıtkı Koçman University, Department of Anesthesiology and Reanimation, Muğla, Turkey.

Muğla Sıtkı Koçman University Training and Research Hospital, Department of Anesthesiology and Reanimation, Muğla, Turkey.

出版信息

J Clin Anesth. 2019 Nov;57:31-36. doi: 10.1016/j.jclinane.2019.03.012. Epub 2019 Mar 6.

Abstract

STUDY OBJECTIVE

Laparoscopic cholecystectomy (LC) is a frequently applied minimally invasive surgery. Intraoperative access is provided with small keyhole entries on the abdominal wall. However, LC causes moderate to severe postoperative pain. The subcostal approach of TAP block was described by Hebbard et al. for postoperative analgesia especially for upper abdominal surgeries. Ultrasound-guided erector spinae plane (US-ESP) block is a novel technique targeting ventral rami, dorsal rami and rami communicantes of the spinal nerves.

DESIGN

Single-blinded, prospective, randomized study.

SETTING

Tertiary university hospital, postoperative recovery room and surgical ward.

PATIENTS

Seventy-six patients (ASA I-II) were divided into two equal groups. After applying the exclusion criteria, 68 patients were included in final analysis (34 patients in ESP group and 34 in OSTAP group).

INTERVENTIONS

Erector spinae plane block was performed in the ESP group and oblique subcostal transversus abdominis block was performed in the OSTAP group.

MEASUREMENTS

Postoperative tramadol consumption and pain scores between groups were compared. In addition, intraoperative fentanyl need was measured.

MAIN RESULTS

Postoperative tramadol consumption was 139.1 ± 21.9 mg in the ESP group and 199.4 ± 27.7 mg in the OSTAP group (mean difference 60.29 mg, 95% confidence interval - 72.40 to - 48.19; p < 0.001). NRS scores at almost all time-points were lower in the ESP group according to the repeated measures analysis. Integration of AUC and Mann Whitney U test results have revealed that there was no time wise difference between ESP and OSTAP groups even though NRS scores by itself and time-wise linear area under curve scores were higher in the OSTAP group compare to ESP group. There were no differences in intraoperative fentanyl need.

CONCLUSION

Ultrasound-guided ESP block reduced postoperative tramadol consumption and pain scores more effectively than OSTAP block after laparoscopic cholecystectomy surgery.

摘要

研究目的

腹腔镜胆囊切除术(LC)是一种常用的微创手术。手术通过腹壁上的小钥匙孔进入。然而,LC 会引起中度至重度的术后疼痛。Hebbard 等人描述了 TAP 阻滞的肋下入路,用于术后镇痛,特别是用于上腹部手术。超声引导竖脊肌平面(US-ESP)阻滞是一种针对脊神经腹侧支、背侧支和交通支的新技术。

设计

单盲、前瞻性、随机研究。

设置

三级大学医院、术后恢复室和外科病房。

患者

76 名(ASA I-II)患者分为两组。应用排除标准后,68 名患者纳入最终分析(ESP 组 34 例,OSTAP 组 34 例)。

干预措施

ESP 组行竖脊肌平面阻滞,OSTAP 组行肋下斜横腹肌阻滞。

测量

比较两组患者术后曲马多的消耗量和疼痛评分。此外,还测量了术中芬太尼的需要量。

主要结果

ESP 组术后曲马多消耗量为 139.1±21.9mg,OSTAP 组为 199.4±27.7mg(平均差异 60.29mg,95%置信区间 -72.40 至 -48.19;p<0.001)。根据重复测量分析,ESP 组几乎所有时间点的 NRS 评分都较低。AUC 整合和 Mann Whitney U 检验结果表明,即使 NRS 评分本身和时间线性曲线下面积评分在 OSTAP 组中高于 ESP 组,ESP 组和 OSTAP 组之间也没有时间差异。术中芬太尼的需要量没有差异。

结论

与 OSTAP 阻滞相比,超声引导 ESP 阻滞可更有效地减少腹腔镜胆囊切除术后患者术后曲马多的消耗和疼痛评分。

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