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室内气溶胶的特定来源暴露和风险评估。

Source specific exposure and risk assessment for indoor aerosols.

机构信息

National Research Centre for the Working Environment, Lersø Parkallé 105, Copenhagen DK-2100, Denmark.

National Centre for Nano Fabrication and Characterization, Technical University of Denmark, Fysikvej 307, 2800 Kgs. Lyngby, Denmark.

出版信息

Sci Total Environ. 2019 Jun 10;668:13-24. doi: 10.1016/j.scitotenv.2019.02.398. Epub 2019 Mar 1.

DOI:10.1016/j.scitotenv.2019.02.398
PMID:30851679
Abstract

Poor air quality is a leading contributor to the global disease burden and total number of deaths worldwide. Humans spend most of their time in built environments where the majority of the inhalation exposure occurs. Indoor Air Quality (IAQ) is challenged by outdoor air pollution entering indoors through ventilation and infiltration and by indoor emission sources. The aim of this study was to understand the current knowledge level and gaps regarding effective approaches to improve IAQ. Emission regulations currently focus on outdoor emissions, whereas quantitative understanding of emissions from indoor sources is generally lacking. Therefore, specific indoor sources need to be identified, characterized, and quantified according to their environmental and human health impact. The emission sources should be stored in terms of relevant metrics and statistics in an easily accessible format that is applicable for source specific exposure assessment by using mathematical mass balance modelings. This forms a foundation for comprehensive risk assessment and efficient interventions. For such a general exposure assessment model we need 1) systematic methods for indoor aerosol emission source assessment, 2) source emission documentation in terms of relevant a) aerosol metrics and b) biological metrics, 3) default model parameterization for predictive exposure modeling, 4) other needs related to aerosol characterization techniques and modeling methods. Such a general exposure assessment model can be applicable for private, public, and occupational indoor exposure assessment, making it a valuable tool for public health professionals, product safety designers, industrial hygienists, building scientists, and environmental consultants working in the field of IAQ and health.

摘要

空气质量差是导致全球疾病负担和全球死亡人数增加的主要原因之一。人类大部分时间都在室内环境中度过,而大部分吸入暴露都发生在室内。室内空气质量(IAQ)受到通过通风和渗透进入室内的室外空气污染以及室内排放源的挑战。本研究旨在了解改善室内空气质量的有效方法的现有知识水平和差距。排放法规目前主要针对室外排放,而对室内源排放的定量理解通常缺乏。因此,需要根据其对环境和人类健康的影响来识别、表征和量化特定的室内源。排放源应根据相关指标和统计数据进行存储,并以易于访问的格式存储,以便使用数学质量平衡模型进行针对特定源的暴露评估。这为综合风险评估和有效的干预措施奠定了基础。对于这种一般的暴露评估模型,我们需要 1)用于室内气溶胶排放源评估的系统方法,2)以相关的 a)气溶胶指标和 b)生物指标表示的源排放文件,3)用于预测性暴露建模的默认模型参数化,4)与气溶胶特性技术和建模方法相关的其他需求。这种一般的暴露评估模型可适用于私人、公共和职业室内暴露评估,使其成为从事室内空气质量和健康领域的公共卫生专业人员、产品安全设计师、工业卫生学家、建筑科学家和环境顾问的有价值工具。

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