Dempsey Robert F, Monson Laura A, Maricevich Renata S, Truong Tuan A, Olarunnipa Shola, Lam Sandi K, Dauser Robert C, Hollier Larry H, Buchanan Edward P
Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, 6701 Fannin Street, CC 610.00, Houston, TX 77030, USA.
Department of Neurosurgery, Baylor College of Medicine, 6701 Fannin Street, CC 1230.01, Houston, TX 77030, USA.
Clin Plast Surg. 2019 Apr;46(2):123-139. doi: 10.1016/j.cps.2018.11.001. Epub 2019 Jan 30.
Nonsyndromic craniosynostosis is significantly more common than syndromic craniosynostosis, affecting the sagittal, coronal, metopic, and lambdoid sutures in decreasing order of frequency. Nonsyndromic craniosynostosis is most frequently associated with only 1 fused suture, creating a predictable head shape. Repair of craniosynostosis is recommended to avoid potential neurodevelopmental delay. Early intervention at 3 to 4 months of age allows minimally invasive approaches, but requires postoperative molding helmet therapy and good family compliance. Open techniques are deferred until the child is older to better tolerate the associated surgical stress. Cranial vault remodeling is generally well-tolerated with a low rate of complications.
非综合征性颅缝早闭比综合征性颅缝早闭明显更常见，按频率递减顺序影响矢状缝、冠状缝、额缝和人字缝。非综合征性颅缝早闭最常仅与一条融合缝相关，形成可预测的头型。建议修复颅缝早闭以避免潜在的神经发育延迟。3至4个月大时进行早期干预可采用微创方法，但术后需要佩戴塑形头盔治疗且家庭配合良好。开放技术则推迟到孩子年龄稍大时进行，以便更好地耐受相关手术应激。颅骨重塑一般耐受性良好，并发症发生率低。
