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帕里-龙贝格综合征

Parry Romberg Syndrome.

作者信息

Schultz Kelly P, Dong Elaine, Truong Tuan A, Maricevich Renata S

机构信息

Division of Plastic Surgery, Baylor College of Medicine, 6701 Fannin Street, Houston, TX 77030.

Division of Plastic Surgery, Baylor College of Medicine, 6701 Fannin Street, Houston, TX 77030.

出版信息

Clin Plast Surg. 2019 Apr;46(2):231-237. doi: 10.1016/j.cps.2018.11.007. Epub 2019 Jan 9.

Abstract

Parry-Romberg syndrome, or progressive hemifacial atrophy, is a rare disorder of unknown etiology. Patients present with unilateral atrophy of skin that may progress to involve underlying fat, muscle, and osseocartilaginous structures. Neurologic complications are common. After self-limited disease stabilization, various reconstructive options may be used to restore patients' facial symmetry. Serial autologous fat grafting has shown favorable results in reconstruction of mild or moderate soft tissue deficiency, but free tissue transfer remains the treatment of choice for severe disease.

摘要

帕里-罗姆伯格综合征,即进行性半侧面部萎缩,是一种病因不明的罕见疾病。患者表现为单侧皮肤萎缩,可能会进展至累及皮下脂肪、肌肉和骨软骨结构。神经系统并发症很常见。在疾病自限性稳定后,可采用各种重建方法来恢复患者面部对称性。连续自体脂肪移植在重建轻度或中度软组织缺损方面已显示出良好效果,但对于严重疾病,游离组织移植仍是首选治疗方法。

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