Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Can J Ophthalmol. 2019 Feb;54(1):87-93. doi: 10.1016/j.jcjo.2018.03.005. Epub 2018 Apr 27.
To report the morphological spectrum and outcome after laser treatment in posterior zone I retinopathy of prematurity.
Retrospective, consecutive, interventional case series.
Review of charts and RetCam images of preterm infants with posterior zone I retinopathy of prematurity (defined as area within a circle, the radius of which extends from the center of the optic disc to the center of the macula) treated with confluent laser at a tertiary care referral institute between January 2006 and December 2015. Data was analyzed and tabulated using frequency and descriptive statistics to describe the demography, morphology, and outcome after laser treatment.
Fifty-six eyes (28 infants) with a mean gestational age of 28.65 ± 2.18 weeks and birth weight of 1153.04 ± 251.51 g were analyzed. Forty-two (75%) eyes had persistent tunica vasculosa lentis and 25 (44.6%) had preretinal hemorrhages. All eyes had circumferential ROP and a poorly developed foveal vasculature. Four distinct morphological patterns were encountered: I - typical aggressive posterior retinopathy was seen in 36 (64.3%) eyes; II - atypical aggressive posterior retinopathy (14 eyes; 25%) had raised fibrovascular proliferation always on the nasal retina close to the optic disc; III - hybrid retinopathy of prematurity (4 eyes; 8.7%) had a mat-like fibrous proliferation on vascularized posterior retina; and IV - threshold retinopathy of prematurity seen in 2 (4.4%) eyes. An unfavourable outcome was seen in 44 (78.6%) eyes.
Retinopathy of prematurity in posterior zone I presents with atypical morphology and poor outcomes despite confluent laser photocoagulation.
报告后极部 1 区早产儿视网膜病变（ROP）经激光治疗后的形态学谱和结果。
回顾性、连续、干预性病例系列。
回顾 2006 年 1 月至 2015 年 12 月在一家三级转诊机构接受融合性激光治疗的后极部 1 区 ROP（定义为以视盘中心为中心、半径延伸至黄斑中心的圆形区域内的区域）的早产儿的图表和 RetCam 图像。使用频率和描述性统计数据对数据进行分析和制表，以描述人口统计学、形态学和激光治疗后的结果。
分析了 56 只眼（28 例婴儿），平均胎龄为 28.65±2.18 周，出生体重为 1153.04±251.51g。42 只眼（75%）有持续性脉络膜血管鞘，25 只眼（44.6%）有视网膜前出血。所有眼睛都有周向 ROP 和发育不良的黄斑血管。发现了 4 种不同的形态学模式：I - 典型侵袭性后部 ROP 见于 36 只眼（64.3%）；II - 非典型侵袭性后部 ROP（14 只眼；25%）在靠近视盘的鼻侧视网膜上始终有隆起的纤维血管增生；III - 早产儿混合型视网膜病变（4 只眼；8.7%）在血管化的后视网膜上有类似毡样的纤维增生；IV - 阈值期早产儿视网膜病变见于 2 只眼（4.4%）。44 只眼（78.6%）预后不良。
尽管进行了融合性激光光凝治疗，但后极部 1 区的 ROP 表现出非典型形态和不良结局。
