Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, MC 8849 Dallas, TX, United States.
Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, MC 8849 Dallas, TX, United States.
Psychiatry Res Neuroimaging. 2019 Apr 30;286:11-17. doi: 10.1016/j.pscychresns.2019.03.002. Epub 2019 Mar 2.
Trust is a fundamental part of human interpersonal relationships, and among other complex factors it is shown to be linked with demographic characteristics and specific regions of the brain. The authors utilized a large, community-based database gathered from the Dallas Heart Study to determine specific brain regions associated with an individual's trust in neighbors. A trust questionnaire was taken and regional brain volumes were determined from structural magnetic resonance imaging. Two analyses using logistic regressions in a training set and validation set were performed to investigate the association between measures of trust and bilateral brain region volumes and thickness. A total of 1527 participants were included in the final analysis. Right caudal anterior cingulate cortex thickness and left caudate volume were inversely correlated with neighbor trust, while left amygdala volume was positively correlated with neighbor trust. Greater age and higher level of education were positively correlated with neighbor trust. African Americans showed less neighbor trust than Caucasians and Hispanics. Anterior cingulate cortex, caudate, and amygdala are all integral parts of the salience network; thus, results of this study suggest that the salience network, the brain network responsible for functions such as communication and social behavior, may play a role in the formation of interpersonal trust.
信任是人类人际关系的一个基本组成部分，它与其他复杂因素有关，与人口统计学特征和大脑的特定区域有关。作者利用从达拉斯心脏研究中收集的一个大型社区数据库，确定与个人对邻居的信任相关的特定大脑区域。进行了信任问卷，并从结构磁共振成像中确定了区域脑容量。在训练集和验证集中使用逻辑回归进行了两项分析，以研究信任测量值与双侧大脑区域体积和厚度之间的关联。共有 1527 名参与者纳入最终分析。右侧尾状前扣带皮层厚度和左侧尾状核体积与邻居信任呈负相关，而左侧杏仁核体积与邻居信任呈正相关。年龄较大和教育程度较高与邻居信任呈正相关。非裔美国人比白人和西班牙裔人对邻居的信任度较低。前扣带皮层、尾状核和杏仁核都是突显网络的重要组成部分；因此，这项研究的结果表明，突显网络，即负责沟通和社交行为等功能的大脑网络，可能在人际信任的形成中发挥作用。
