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EAU Guidelines on Non-Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016.EAU 指南：非肌层浸润性膀胱尿路上皮癌：2016 年更新版。
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Clin Genitourin Cancer. 2015 Oct;13(5):e375-7. doi: 10.1016/j.clgc.2015.03.005. Epub 2015 Mar 30.
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Large cell neuroendocrine carcinoma of the urinary bladder: case report and review.膀胱大细胞神经内分泌癌：病例报告及文献复习
Curr Urol. 2013 Feb;7(3):155-9. doi: 10.1159/000356270. Epub 2014 Feb 10.
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Primary large cell neuroendocrine carcinoma of the ureter.输尿管原发性大细胞神经内分泌癌
Int J Clin Exp Pathol. 2013;6(4):729-36. Epub 2013 Mar 15.
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Pathology of genitourinary malignancies: implications for clinical management.泌尿生殖系统恶性肿瘤病理学：对临床管理的影响。
Semin Oncol Nurs. 2012 Aug;28(3):143-53. doi: 10.1016/j.soncn.2012.05.003.
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Large cell neuroendocrine carcinoma of the urinary bladder. Bibliographic review.膀胱大细胞神经内分泌癌。文献综述。
Arch Esp Urol. 2011 Mar;64(2):105-13.
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Large cell undifferentiated carcinoma of the urinary bladder.膀胱大细胞未分化癌。
Pathology. 2010 Jun;42(4):364-8. doi: 10.3109/00313021003767363.
8
Lymphoepithelial carcinoma versus large cell undifferentiated carcinoma of the major salivary glands.大唾液腺的淋巴上皮癌与大细胞未分化癌的对比
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9
The fine structure of large cell undifferentiated carcinoma of the lung. Evidence for its relation to squamous cell carcinomas and adenocarcinomas.肺大细胞未分化癌的精细结构。其与鳞状细胞癌和腺癌关系的证据。
Hum Pathol. 1978 Mar;9(2):143-56. doi: 10.1016/s0046-8177(78)80105-1.

输尿管原发性大细胞未分化癌。

Primary Large-Cell Undifferentiated Carcinoma of the Ureter.

机构信息

Clinic of Urology Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.

Clinic of Urology Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey,

出版信息

Med Princ Pract. 2019;28(5):481-484. doi: 10.1159/000499467. Epub 2019 Mar 11.

DOI:10.1159/000499467
PMID:30852567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6771049/
Abstract

OBJECTIVE

To report the first case in the literature of a primary large-cell undifferentiated carcinoma (LCUC) of the ureter with a very aggressive behavior and dismal prognosis.

CLINICAL PRESENTATION AND INTERVENTION

A 60-year-old woman with a history of intermittent macroscopic hematuria and mild to moderate right flank pain was admitted to the Department of Urology. Tissue biopsies and cytological samples were taken. Pathologic examination was consistent with LCUC.

CONCLUSION

LCUC of the ureter is an aggressive tumor with a high proliferation index. Patients might be diagnosed at an advanced stage. LCUC must be considered in the differential diagnosis of urinary tract pathologies.

摘要

目的

报告首例输尿管原发性大细胞未分化癌（LCUC）病例，该肿瘤具有非常侵袭性的行为和不良预后。

临床表现和干预

一名 60 岁女性，间歇性出现肉眼血尿和轻至中度右侧腰痛，收入泌尿科。进行了组织活检和细胞学样本采集。病理检查符合 LCUC。

结论

输尿管 LCUC 是一种侵袭性肿瘤，增殖指数高。患者可能在晚期被诊断。在鉴别诊断尿路病变时必须考虑 LCUC。