Rongen-Westerlaken C, Oostdijk W, van Gelderen H H
Tijdschr Kindergeneeskd. 1986 Feb;54(1):15-9.
The various causes of persisting hyperthyroxinemia without hyperthyroidism are discussed after short case histories of an infant with hyperthyroxinemia due to TBG excess, discovered by newborn screening for congenital hypothyroidism and a girl with peripheral resistance to thyroid hormones disclosed by investigation of a small goiter. The differentiation of these various causes by thyroid function-tests is indicated. Though the anomalies leading to euthyroid hyperthyroxinemia are usually harmless their timely recognition, also in other members of the family, will prevent erroneous diagnosis and treatment of hyperthyroidism.
在介绍了两例病例的简短病史后,讨论了无甲状腺功能亢进情况下持续存在高甲状腺素血症的各种原因。第一例是一名因甲状腺素结合球蛋白(TBG)过多导致高甲状腺素血症的婴儿,通过新生儿先天性甲状腺功能减退筛查发现;第二例是一名女孩,因小甲状腺肿检查发现外周甲状腺激素抵抗。文中指出了通过甲状腺功能测试对这些不同原因进行鉴别。虽然导致甲状腺功能正常的高甲状腺素血症的异常情况通常无害,但及时识别这些异常情况,包括在家族中的其他成员中识别,将避免对甲状腺功能亢进的错误诊断和治疗。