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促甲状腺激素释放激素(TRH)对脊髓小脑变性患者姿势图的急慢性影响。

Acute and chronic effects of thyrotropin-releasing hormone (TRH) on stabilogram in spinocerebellar degenerations.

作者信息

Yoshida M, Nakanishi T, Komatsu Y

出版信息

Tohoku J Exp Med. 1986 Mar;148(3):327-31. doi: 10.1620/tjem.148.327.

DOI:10.1620/tjem.148.327
PMID:3085285
Abstract

A single blind cross over trial was conducted of thyrotropin-releasing hormone treatment in 7 patients with spinocerebellar degenerations. Patients received daily 2 mg of thyrotropin releasing hormone intramuscularly during the 2 week treatment period. Acute beneficial effect on stabilogram was demonstrated, but significant therapeutic efficacy in the chronic treatment failed to be demonstrated, though a trend of effectiveness was observed.

摘要

对7例脊髓小脑变性患者进行了促甲状腺激素释放激素治疗的单盲交叉试验。在为期2周的治疗期间,患者每天接受2毫克促甲状腺激素释放激素肌肉注射。结果显示对稳定图有急性有益作用,但在慢性治疗中未能证明有显著的治疗效果,不过观察到了一种有效的趋势。

相似文献

1
Acute and chronic effects of thyrotropin-releasing hormone (TRH) on stabilogram in spinocerebellar degenerations.促甲状腺激素释放激素(TRH)对脊髓小脑变性患者姿势图的急慢性影响。
Tohoku J Exp Med. 1986 Mar;148(3):327-31. doi: 10.1620/tjem.148.327.
2
[Clinical studies of spinocerebellar degeneration].
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Controlled trial of thyrotropin releasing hormone tartrate in ataxia of spinocerebellar degenerations.酒石酸促甲状腺激素释放激素治疗脊髓小脑变性共济失调的对照试验
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[Analysis of the abnormal ocular movements in spinocerebellar degenerations and the influence of the thyrotropin releasing hormone (author's transl)].
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[Spinocerebellar degenerations].
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Motor disabilities and effects of thyrotropin-releasing hormone on ataxia of spinocerebellar degeneration.运动障碍以及促甲状腺激素释放激素对脊髓小脑变性共济失调的影响。
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