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一种测定霉菌毒素的生物学方法——梨形四膜虫

[A biological method for the determination of mycotoxins--Tetrahymena pyriformis].

作者信息

Nistiar F, Hrusovský J, Mojzis J, Mizik P, Nistiarová A

出版信息

Vet Med (Praha). 1986 Apr;31(4):245-50.

PMID:3085318
Abstract

The toxic action of selected mycotoxins on a biological subject was tested in the protozoan Tetrahymena pyriformis. The following toxins were tested: toxin T-2 at doses from 1.52 micrograms to 100.0 mg per litre of medium, ochratoxin A at doses from 12.21 micrograms to 800.0 mg per litre of medium, and rubratoxin B at doses from 12.21 micrograms to 800.0 mg per litre of medium. In toxin T-2 the LD100 was found to be about 390.63 micrograms and LD50 about 48.83 micrograms per litre of medium. In ochratoxin A the LD100 was about 25.0 mg and LD50 about 3.13 mg per litre of medium. In rubratoxin B the LD100 was about 200.0 mg and LD50 about 25.0 mg per litre of medium.

摘要

在梨形四膜虫中测试了某些霉菌毒素对生物对象的毒性作用。测试了以下毒素:毒素T-2,剂量为每升培养基1.52微克至100.0毫克;赭曲霉毒素A,剂量为每升培养基12.21微克至800.0毫克;以及红天精毒素B,剂量为每升培养基12.21微克至800.0毫克。发现毒素T-2的每升培养基LD100约为390.63微克,LD50约为48.83微克。赭曲霉毒素A的每升培养基LD100约为25.0毫克,LD50约为3.13毫克。红天精毒素B的每升培养基LD100约为200.0毫克,LD50约为25.0毫克。

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