[A biological method for the determination of mycotoxins--Tetrahymena pyriformis].

The toxic action of selected mycotoxins on a biological subject was tested in the protozoan Tetrahymena pyriformis. The following toxins were tested: toxin T-2 at doses from 1.52 micrograms to 100.0 mg per litre of medium, ochratoxin A at doses from 12.21 micrograms to 800.0 mg per litre of medium, and rubratoxin B at doses from 12.21 micrograms to 800.0 mg per litre of medium. In toxin T-2 the LD100 was found to be about 390.63 micrograms and LD50 about 48.83 micrograms per litre of medium. In ochratoxin A the LD100 was about 25.0 mg and LD50 about 3.13 mg per litre of medium. In rubratoxin B the LD100 was about 200.0 mg and LD50 about 25.0 mg per litre of medium.