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体外比较 4 种预装式眼内透镜注吸系统在角膜和巩膜切口的输送性能。

In vitro comparison of delivery performance of 4 preloaded intraocular lens injector systems for corneal and sclerocorneal incisions.

机构信息

Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.

Research and Development, Alcon Laboratories, Inc., Fort Worth, Texas, USA.

出版信息

J Cataract Refract Surg. 2019 Jun;45(6):840-846. doi: 10.1016/j.jcrs.2018.10.050. Epub 2019 Mar 8.

Abstract

PURPOSE

To compare preloaded intraocular lens (IOL) injector systems in porcine eyes.

SETTING

Alcon Japan, Tokyo, Japan.

DESIGN

Experimental study.

METHODS

Freshly-excised porcine eyes were assigned to 11 study groups (10 eyes per group) consisting of UltraSert (system U: corneal incisions 2.2 mm and 2.4 mm), UltraSert long tip (system ULT: corneal incision 2.6 mm; sclerocorneal incisions 2.4 mm and 2.6 mm), iTec (system iT: corneal incisions 2.2 mm and 2.4 mm; sclerocorneal incisions 2.2 mm and 2.4 mm), and Vivinex iSert (system iS: corneal incision 2.0 mm; sclerocorneal incision 1.8 mm).

RESULTS

There were a few cases with IOL adherence to the plunger tip, delayed trailing haptic, intrawound manipulation, and damage to IOL, although the occurrence was not confined to particular devices. Cartridge tip splitting was observed with system iS. System U 2.4 mm and system ULT 2.6 mm caused the least amount of incision enlargement for corneal and sclerocorneal incisions, respectively. System ULT 2.6 mm resulted in the largest final size for corneal incisions and sclerocorneal incisions. System iS induced the largest amount of incision enlargement for both incisions but had significantly smaller final incision size than all other systems for corneal incisions and sclerocorneal incisions, except for system U 2.2 mm for corneal incisions.

CONCLUSIONS

Intraocular lens implantation through a tighter incision and with cartridge-insertion technique (>wound-assisted technique) caused greater wound enlargement. A smaller preimplantation incision with a preloaded IOL delivery system did not necessarily result in significantly smaller final incision because of wound enlargement.

摘要

目的

比较预装式人工晶状体(IOL)注射器系统在猪眼内的效果。

设置

日本爱尔康公司,日本东京。

设计

实验研究。

方法

将新鲜取出的猪眼分为 11 个研究组(每组 10 只眼),包括 UltraSert(系统 U:角膜切口 2.2mm 和 2.4mm)、UltraSert 长尖端(系统 ULT:角膜切口 2.6mm;巩膜角膜切口 2.4mm 和 2.6mm)、iTec(系统 iT:角膜切口 2.2mm 和 2.4mm;巩膜角膜切口 2.2mm 和 2.4mm)和 Vivinex iSert(系统 iS:角膜切口 2.0mm;巩膜角膜切口 1.8mm)。

结果

尽管并非仅限于特定装置,但仍有少数情况下 IOL 与柱塞尖端粘连、延迟尾随襻、眼内操作和 IOL 损坏。系统 iS 观察到卡匣尖端分裂。对于角膜和巩膜切口,系统 U 2.4mm 和系统 ULT 2.6mm 分别导致切口扩大最小。系统 ULT 2.6mm 导致角膜切口和巩膜角膜切口的最终切口尺寸最大。系统 iS 引起的切口扩大量最大,但对于角膜和巩膜切口,除了系统 U 2.2mm 外,其最终切口尺寸明显小于所有其他系统。

结论

通过更紧密的切口和卡匣插入技术(>辅助切口技术)植入人工晶状体会导致更大的切口扩大。具有预装式 IOL 输送系统的更小的预植入切口不一定会导致最终切口尺寸显著减小,因为会发生切口扩大。

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