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响应性顺磁性化学交换饱和转移磁共振成像造影剂。

Responsive paramagnetic chemical exchange saturation transfer MRI contrast agents.

作者信息

Pagel Mark D

机构信息

Department of Biomedical Engineering, Arizona Cancer Center, University of Arizona, Tucson, AZ, USA and Department of Chemistry & Biochemistry, Arizona Cancer Center, University of Arizona, Tucson, AZ, USA.

出版信息

Imaging Med. 2011;3(4):377-380. doi: 10.2217/IIM.11.29.

Abstract

"The ability of PARACEST agents to provide molecular-level information has great potential to predict therapeutic effects before initiating the therapy and earlier assessments of therapeutic effects soon after initiating therapy, in order to contribute to personalized medicine in the clinic."

摘要

PARACEST造影剂提供分子水平信息的能力,在治疗开始前预测治疗效果以及在治疗开始后不久对治疗效果进行早期评估方面具有巨大潜力,从而有助于临床中的个性化医疗。

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