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[透明质酸酶活性脑膜炎球菌携带者的流行病学意义]

[Epidemiological significance of carriers of hyaluronidase-active meningococci].

作者信息

Mironova T K, Maslovskaia G Ia, Tatarnikov V M, Kostiukova N N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1986 Jan(1):52-4.

PMID:3085405
Abstract

To find out the epidemiological role of the carriers of hyaluronidase-positive meningococcal strains, their spread in the foci of meningococcal infection, as well as outside these foci, was studied. For this purpose, altogether 5059 persons from 40 family foci of infection and 40 organized groups were examined. The number of carriers of hyaluronidase-active meningococci, detected among those of them who had contacts with sick persons, was 13 times greater than among the persons having no such contacts. In preschool institutions with unfavorable morbidity situation this number was 16 times greater than in those with favorable situation. In the family foci carriers of hyaluronidase-active meningococci constituted 80-88 %. The percentage of the carriers of hyaluronidase-active meningococci causing cases of the generalized form of meningococcal infection varied in different groups. According to the results obtained in this study, the threshold percentage of such carriers constituted 30 in preschool institutions, 36 in boarding schools and 50 in common school and in hostels for adults.

摘要

为了查明透明质酸酶阳性脑膜炎球菌菌株携带者的流行病学作用,研究了它们在脑膜炎球菌感染病灶以及这些病灶之外的传播情况。为此,共对来自40个家庭感染病灶和40个有组织群体的5059人进行了检查。在与病人有接触的人群中检测到的透明质酸酶活性脑膜炎球菌携带者数量,比没有这种接触的人群中高13倍。在发病情况不利的学前机构中,这一数字比情况有利的机构高16倍。在家庭感染病灶中,透明质酸酶活性脑膜炎球菌携带者占80%-88%。导致脑膜炎球菌感染全身性病例的透明质酸酶活性脑膜炎球菌携带者百分比在不同群体中有所不同。根据本研究获得的结果,此类携带者的阈值百分比在学前机构中为30%,在寄宿学校中为36%,在普通学校和成人宿舍中为50%。

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