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非参数统计检验用于检验指数性在医学研究中的应用。

Non-parametric statistical test for testing exponentiality with applications in medical research.

机构信息

Department of Basic Science, Faculty of Engineering, The British University in Egypt, El Sherouk City, Cairo, Egypt.

出版信息

Stat Methods Med Res. 2020 Feb;29(2):413-420. doi: 10.1177/0962280218824979. Epub 2019 Mar 10.

Abstract

The aim of designing the non-parametric statistical test in this paper is to assess some treatment methods by studying the failure behavior of the observed survival data. A treatment method represents the application of different healthcare interventions for the cure or reduction of disease-related symptoms. The survival times of patients are registered after applying the proposed treatment method. The behavior of the observed data in this paper is assumed to enjoy an increasing failure rate or constant failure rate (exponential case) property. If the survival data have increasing failure rate property, then the proposed treatment method is useless (has negative influence on patients) and another method should be recommended, while if the collected data have exponential property, then the proposed treatment method has no positive or negative influence on patients. To guarantee a right assessment using the proposed statistical test, its efficiency and power are calculated and compared with other tests. The proposed statistical test is applied in case of some cancer treatments.

摘要

本文设计非参数统计检验的目的是通过研究观察生存数据的失效行为来评估某些治疗方法。一种治疗方法代表了应用不同的医疗干预措施来治疗或减轻与疾病相关的症状。在应用所提出的治疗方法后,记录患者的生存时间。本文中观察数据的行为假定具有递增失效率或恒定失效率(指数情况)特性。如果生存数据具有递增失效率特性,那么所提出的治疗方法是无用的(对患者有负面影响),应该推荐另一种方法,而如果收集的数据具有指数特性,那么所提出的治疗方法对患者没有正面或负面影响。为了使用所提出的统计检验进行正确的评估,计算并比较了其效率和功效与其他检验。所提出的统计检验应用于某些癌症治疗的情况。

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