Meucci Francesco, Stolcova Miroslava, De Marco Federico, Mattesini Alessio, Ristalli Francesca, Chiriatti Niccolò, Squillantini Giovanni, Agostini Cecilia, Sarti Cristina, Di Mario Carlo
Interventistica Cardiologica Strutturale, Dipartimento Cardio-Toraco-Vascolare, AOU Careggi, Firenze.
Dipartimento di Cardiologia, IRCCS Policlinico San Donato, San Donato Milanese (MI).
G Ital Cardiol (Rome). 2019 Mar;20(3 Suppl 1):9S-16S. doi: 10.1714/3121.31036.
Percutaneous patent foramen ovale (PFO) closure is an intervention aimed to prevent cardioembolic stroke. It recently proved to be superior to antiplatelet therapy in preventing recurrent strokes in a well-selected population of patients with a previous cryptogenic cerebral ischemic event. A large part of the clinical advantage of PFO transcatheter therapy derives from the very high efficacy and safety of the maneuver. Various types of devices with different characteristics are currently available for the use of the interventionists. Recently, a direct PFO suture device has been added to the device list, allowing for PFO closure without implanting any prosthesis. This article describes the procedure of PFO closure with a particular focus on the main characteristics of the various devices available. A road-map of choice among the various prostheses is also provided, keeping in mind the patient's clinical features and the various PFO anatomies.