Sperlongano Simona, Giordano Mario, Ciccarelli Giovanni, Bassi Giuseppe, Malvezzi Caracciolo D'Aquino Marco, Del Giudice Carmen, Gaio Gianpiero, D'Andrea Antonello, Postolache Adriana, Cappelli Bigazzi Maurizio, Scognamiglio Giancarlo, Sarubbi Berardo, Russo Maria Giovanna, Golino Paolo, Lancellotti Patrizio
Division of Cardiology, Department of Traslational Medical Sciences, University of Campania Luigi Vanvitelli, 80131 Naples, Italy.
Division of Pediatric Cardiology, University of Campania Luigi Vanvitelli, Monaldi Hospital, 80131 Naples, Italy.
J Clin Med. 2022 Jul 11;11(14):4001. doi: 10.3390/jcm11144001.
Percutaneous patent foramen ovale (PFO) closure by traditional, double disc occluder devices was shown to be safe for patients with PFO, and more effective than prolonged medical therapy in preventing recurrent thromboembolic events. The novel suture-mediated "deviceless" PFO closure system overcomes most of the risks and limitations associated with the traditional PFO occluders, appearing to be feasible in most interatrial septum anatomies, even if data about its long-term effectiveness and safety are still lacking. The aim of the present review was to provide to the reader the state of the art about the traditional and newer techniques of PFO closure, focusing both on the procedural aspects and on the pivotal role of transesophageal echocardiography (TEE) in patient's selection, peri-procedural guidance, and post-interventional follow-up.
传统双盘封堵器经皮闭合卵圆孔未闭(PFO)对PFO患者显示是安全的,并且在预防复发性血栓栓塞事件方面比长期药物治疗更有效。新型缝线介导的“无器械”PFO闭合系统克服了与传统PFO封堵器相关的大多数风险和局限性,即使在大多数房间隔解剖结构中似乎都是可行的,尽管关于其长期有效性和安全性的数据仍然缺乏。本综述的目的是向读者提供PFO闭合的传统和新技术的最新进展,重点关注操作方面以及经食管超声心动图(TEE)在患者选择、围手术期指导和介入后随访中的关键作用。