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一名接受支气管镜检查儿童的肺曲霉菌病相关性支气管结石症诊断:病例报告

Diagnosis of pulmonary aspergillosis-related broncholithiasis in a child undergoing bronchoscopy: A case report.

作者信息

Meng Chen, Zhang Zhongxiao, Liu Xia, Yan Xiuli, Shi Chong, Liu Na, Wang Xinxin, Ma Jing

机构信息

Department of Respiratory Intervention, Ji'nan Children's Hospital, Qilu Children's Hospital of Shandong University, Jinan, Shandong, China.

出版信息

Medicine (Baltimore). 2019 Mar;98(10):e14623. doi: 10.1097/MD.0000000000014623.

DOI:10.1097/MD.0000000000014623
PMID:30855447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6417638/
Abstract

RATIONALE

Broncholithiasis is a rare disease and is characterized by calcification in the tracheobronchial tree. This disease has a predilection in the adult and occurrence is rare in children. Considering its infrequency, we report a rare clinical case, with the aim of sharing our experience during the diagnosis and treatment procedures.

PATIENT CONCERNS

We report a 9-year- and 6-month-old girl who complained of chronic cough and recurrent wheeze for 2 months.

DIAGNOSIS

Bronchialithiasis were found under bronchoscope. Pathologic examination revealed aspergillosis.

INTERVENTIONS

The stone and surrounding granulation tissue were removed using a bronchoscope and the patient was treated with antifungal therapy.

OUTCOMES

The patient was in good general health without any clinical symptoms during the follow-up period.

LESSONS

Pulmonary Aspergillus infection can cause bronchiolithiasis. Stones were removed under bronchoscope, and anti-Aspergillus therapy was effective.

摘要

理论依据

支气管结石症是一种罕见疾病,其特征为气管支气管树钙化。这种疾病好发于成年人,儿童发病罕见。鉴于其罕见性,我们报告一例罕见临床病例,旨在分享我们在诊断和治疗过程中的经验。

患者情况

我们报告一名9岁6个月大的女孩,她主诉慢性咳嗽和反复喘息2个月。

诊断

支气管镜检查发现支气管结石症。病理检查显示为曲霉菌病。

干预措施

使用支气管镜取出结石及周围肉芽组织,并对患者进行抗真菌治疗。

结果

随访期间患者总体健康状况良好,无任何临床症状。

经验教训

肺部曲霉菌感染可导致支气管结石症。通过支气管镜取出结石,抗曲霉菌治疗有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/ff67dfbbefe5/medi-98-e14623-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/fdb4edb2ee69/medi-98-e14623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/128786c6834c/medi-98-e14623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/4f6fbe58f594/medi-98-e14623-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/fd7f89158369/medi-98-e14623-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/ff67dfbbefe5/medi-98-e14623-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/fdb4edb2ee69/medi-98-e14623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/128786c6834c/medi-98-e14623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/4f6fbe58f594/medi-98-e14623-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/fd7f89158369/medi-98-e14623-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b99/6417638/ff67dfbbefe5/medi-98-e14623-g005.jpg

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Indian J Crit Care Med. 2016 Jul;20(7):421-4. doi: 10.4103/0972-5229.186228.
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Broncholithiasis From Histoplasmosis in a Pediatric Patient: Case Reports and Review of Literature.
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Broncholithiasis Assessed by Bronchoscopic Saline Solution Injection.经支气管镜注射生理盐水评估支气管结石症
Intern Med. 2015;54(12):1527-30. doi: 10.2169/internalmedicine.54.3722. Epub 2015 Jun 15.
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Diagnosis and Treatment Evaluation of 48 Cases of Broncholithiasis.48例支气管结石症的诊断与治疗评估
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Classification of broncholiths and clinical outcomes.支气管结石的分类和临床结果。
Respirology. 2013 May;18(4):637-42. doi: 10.1111/resp.12060.