Suppr超能文献

气管支气管异物吸入患儿下呼吸道感染的危险因素

Risk factors for lower respiratory tract infection in children with tracheobronchial foreign body aspiration.

作者信息

Zhong Bing, Sun Si-Lu, Du Jin-Tao, Deng Di, Liu Feng, Liu Ya-Feng, Shi-Xi Liu, Chen Fei

机构信息

Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University.

State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral Medicine of West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

出版信息

Medicine (Baltimore). 2019 Mar;98(10):e14655. doi: 10.1097/MD.0000000000014655.

Abstract

The aim of this study was to determine the risk factors for lower respiratory tract infection (LRTI) in children caused by tracheobronchial foreign body aspiration (TFBA).A total of 351 patients were retrospectively reviewed; all patients were diagnosed with TFBA at West China Hospital of Sichuan University from 2015 to 2017. Univariate analyses and multivariate analysis were used.Age (<2 years) (P < .001), type of foreign body (plant) (P < .001), shape of foreign body (nonsmooth) (P < .001), and residence time of foreign body (>7 days) (P = .001) were risk factors for LRTI on univariate analysis. Multivariate analysis showed age (<2 years) (hazard ratio [HR] = 4.457; 95% confidence interval [CI] = 2.031-6.884; P < .001), type of foreign body (plant) (HR = 2.686; 95% CI = 1.577-3.452; P < .001), shape of foreign body (nonsmooth) (HR = 1.649; 95% CI = 1.437-3.663; P < .008), and residence time of foreign body (>7 days) (HR = 1.751; 95% CI = 1.329-3.554; P = .004) were independent risk factors for LRTI. Furthermore, children with LRTI also had longer lengths of hospital stays and antibiotic use than did children without LRTI.Age, plant foreign body, nonsmooth foreign body, and long-term incarceration were all independent risk factors for LRTI in children. These results can help us to select more appropriate intervention times and stratified treatment for children with TFBA.

摘要

本研究旨在确定气管支气管异物吸入(TFBA)所致儿童下呼吸道感染(LRTI)的危险因素。回顾性分析了351例患者;所有患者均于2015年至2017年在四川大学华西医院被诊断为TFBA。采用单因素分析和多因素分析。单因素分析显示,年龄(<2岁)(P<0.001)、异物类型(植物)(P<0.001)、异物形状(不光滑)(P<0.001)和异物停留时间(>7天)(P=0.001)是LRTI的危险因素。多因素分析显示,年龄(<2岁)(风险比[HR]=4.457;95%置信区间[CI]=2.031-6.884;P<0.001)、异物类型(植物)(HR=2.686;95%CI=1.577-3.452;P<0.001)、异物形状(不光滑)(HR=1.649;95%CI=1.437-3.663;P<0.008)和异物停留时间(>7天)(HR=1.751;95%CI=1.329-3.554;P=0.004)是LRTI的独立危险因素。此外,与无LRTI的儿童相比,LRTI儿童的住院时间和抗生素使用时间也更长。年龄、植物性异物、不光滑异物和长期嵌顿均是儿童LRTI的独立危险因素。这些结果有助于我们为TFBA儿童选择更合适的干预时机和分层治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/136e/6417600/ab8edf0d5be1/medi-98-e14655-g004.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验