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1990 - 2016年创伤性脑损伤临床康复研究的范围综述

Scoping review of clinical rehabilitation research pertaining to traumatic brain injury: 1990-2016.

作者信息

Gerber Lynn H, Bush Haley, Cai Cindy, Garfinkel Steven, Chan Leighton, Cotner Bridget, Wagner Amy

机构信息

Director of Research, Department of Medicine, Fairfax Medical Campus Inova Health System, Falls Church, VA, USA.

Beatty Center for Liver Disease and Obesity, Fairfax Medical Campus Inova Health System, Falls Church, VA, USA.

出版信息

NeuroRehabilitation. 2019;44(2):207-215. doi: 10.3233/NRE-182599.

Abstract

INTRODUCTION

Understanding the impact of disease on function and improving functional outcomes is an important goal of rehabilitation. This scoping review analyzes 25 years of published traumatic brain injury (TBI) clinical rehabilitation research (CRR) to determine the frequency with which function is a research goal.

METHODS

The review protocol was prepared by experienced clinical researchers in the field. We used these search terms: "moderate traumatic brain injury" and "severe traumatic brain injury" and "functional outcomes"; and "rehabilitation" and "educational outcomes" or "cognition" or "community roles" or "community integration" "behavior" or "neuropsychology" or "quality of life", or "vocational outcomes" or "work" or "return to work". Publications from January 1, 1990-December 31, 2016 were included.

RESULTS

1,815 articles met initial criteria, of which 202 were intervention studies, 84 were randomized controlled trials and 353 prospective non-intervention studies. The combination of intervention and prospective non-intervention studies (n = 555) were analyzed for the kind of measurement tools used. Impairment measures (60%) and symptom measures (43%) either singly or in combination were most frequently used. Measures of function were employed in fewer than 30%. For single outcomes, 95 publications used impairment measures, 60 used symptoms and only18 used function. There were 117 studies that used neurocognitive measures. Participation/societal integration evaluation tools were used for community integration(n = 77) employment (n = 50) and independent living status (n = 37).

DISCUSSION

This scoping review identifies a need for additional types of clinical research in the field of TBI CRR. Much of the research is aimed at mitigating impairment and controlling symptoms rather than promoting function. Future efforts by the CRR community studying TBI should address this need.

摘要

引言

了解疾病对功能的影响并改善功能结局是康复的一个重要目标。本综述分析了25年发表的创伤性脑损伤(TBI)临床康复研究(CRR),以确定功能作为研究目标的频率。

方法

该综述方案由该领域经验丰富的临床研究人员制定。我们使用了以下检索词:“中度创伤性脑损伤”、“重度创伤性脑损伤”和“功能结局”;以及“康复”和“教育结局”或“认知”或“社区角色”或“社区融入”“行为”或“神经心理学”或“生活质量”,或“职业结局”或“工作”或“重返工作岗位”。纳入了1990年1月1日至2016年12月31日发表的文献。

结果

1815篇文章符合初始标准,其中202篇为干预研究,84篇为随机对照试验,353篇为前瞻性非干预研究。对干预研究和前瞻性非干预研究的组合(n = 555)分析了所使用的测量工具类型。损伤测量(60%)和症状测量(43%)单独或联合使用最为频繁。功能测量的使用不到30%。对于单一结局,95篇出版物使用损伤测量,60篇使用症状测量,仅18篇使用功能测量。有117项研究使用了神经认知测量。参与/社会融入评估工具用于社区融入(n = 77)、就业(n = 50)和独立生活状况(n = 37)。

讨论

本综述确定了TBI CRR领域需要其他类型的临床研究。大部分研究旨在减轻损伤和控制症状,而非促进功能。CRR社区研究TBI的未来努力应满足这一需求。

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