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对治疗中重度创伤性脑损伤患者的临床实践指南的叙述性综述。

Narrative review of clinical practice guidelines for treating people with moderate or severe traumatic brain injury.

机构信息

Department of Health Administration and Policy, George Mason University, Fairfax, VA, USA.

Medicine Service Line, Inova Health System, Falls Church, VA, USA.

出版信息

NeuroRehabilitation. 2021;48(4):451-467. doi: 10.3233/NRE-210024.

Abstract

BACKGROUND

Practice guidelines (CPGs) provide informed treatment recommendations from systematic reviews and assessment of the benefits and harms that are intended to optimize patient care. Review of CPGs addressing rehabilitation for people with moderate/severe traumatic brain injury (TBI), has not been fully investigated.

OBJECTIVE

Identify published, vetted, clinical practice guidelines that address rehabilitation for people with moderate/severe TBI.

METHODS

Six data bases were accessed using key word search terms: "Traumatic Brain Injury" and "Clinical Practice Guidelines" and "Rehabilitation". Further inclusions included "adult" and "moderate or severe". Exclusions included: "mild" and "concussive injury". Three reviewers read abstracts and manuscripts for final inclusion. The AGREE II template was applied for additional appraisal.

RESULTS

There were 767 articles retrieved using the search terms, 520 were eliminated because of content irrelevance; and 157 did not specify rehabilitation treatment or did not follow a process for CPGs. A total of 17 CPGs met all criteria and only 4 of these met all AGREE II criteria.

CONCLUSION

There are few CPGs addressing rehabilitation for people with moderate/severe TBI. More interventional trials are needed to determine treatment effectiveness. Timely and methodologically sound vetting of studies are needed to ensure CPG reliability and facilitate access to quality, effective treatment for people with moderate/severe TBI.

摘要

背景

实践指南(CPGs)提供了系统评价和利益与危害评估的知情治疗建议,旨在优化患者护理。对针对中度/重度创伤性脑损伤(TBI)患者康复的 CPG 进行的审查尚未得到充分研究。

目的

确定已发表、经过审查的针对中度/重度 TBI 患者康复的临床实践指南。

方法

使用关键词搜索词“创伤性脑损伤”和“临床实践指南”和“康复”访问了六个数据库。进一步的纳入标准包括“成人”和“中度或重度”。排除标准包括:“轻度”和“震荡性损伤”。三名审查员阅读摘要和手稿以进行最终纳入。应用 AGREE II 模板进行了额外的评估。

结果

使用搜索词检索到 767 篇文章,其中 520 篇因内容不相关而被排除在外;157 篇没有具体说明康复治疗或没有遵循 CPG 制定过程。共有 17 项 CPG 符合所有标准,只有 4 项符合所有 AGREE II 标准。

结论

针对中度/重度 TBI 患者康复的 CPG 很少。需要更多的干预试验来确定治疗效果。需要及时且方法正确地审查研究,以确保 CPG 的可靠性,并为中度/重度 TBI 患者提供优质、有效的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e53/8293642/0541211a0584/nre-48-nre210024-g001.jpg

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