Department of Pharmacy, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, China.
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Nat Prod Res. 2020 Apr;34(7):903-908. doi: 10.1080/14786419.2018.1538222. Epub 2019 Mar 11.
A new allo-cedrane sesquiterpene glycoside () and nine known compounds (-) were isolated from the ethanol extract of the fruit of Maxim. Their structures were elucidated by spectroscopic methods, including 1D-, 2D-NMR, and HRESIMS. The absolute configuration of compound was confirmed by CD experiments. Among them, compounds , , , and displayed moderate anti-inflammatory activities by use of an in vitro bioassay.
从三叶木通果实的乙醇提取物中分离得到了一个新的 allo-cedrane 倍半萜糖苷()和九个已知化合物(-)。通过包括 1D-NMR、2D-NMR 和 HRESIMS 在内的光谱方法阐明了它们的结构。通过 CD 实验确定了化合物的绝对构型。其中,化合物、、、和表现出中等的抗炎活性,这是通过体外生物测定得到的。