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[大鼠前庭性眼球震颤的特征]

[Characteristics of vestibular nystagmus in rats].

作者信息

Shipov A A, Ovechkin V G

出版信息

Kosm Biol Aviakosm Med. 1978 Sep-Oct;12(5):68-72.

PMID:308575
Abstract

As a result of experiments on Wistar, Wistar-SPF and mongrel rats, the duration, number of beats and frequency of nystagmus in response to progressively increasing acceleration of 10, 20, 30 and 40 deg/sec2 for 3 sec at each step were determined. These parameters were found to increase with a rise in acceleration, the rate of increase being gradually slowed down (the slope of the curves decreased). The number of beats and the duration of the nystagmus in the Wistar and mongrel rats were identical and significantly higher (P less than 0.01) than those in the Wistar-SPF rats. There was no difference in the nystagmic frequency. It was demonstrated that the system of animal restraint produced a noticeable effect on the quantitative characteristics of the nystagmus, e. g. duration and number of beats. The paper describes a system of gentle restraint of rats.

摘要

通过对Wistar大鼠、Wistar无特定病原体大鼠和杂种大鼠进行实验,测定了在每次以10、20、30和40度/秒²的加速度递增并持续3秒的情况下,眼球震颤的持续时间、搏动次数和频率。发现这些参数随着加速度的增加而增加,增加速率逐渐减慢(曲线斜率减小)。Wistar大鼠和杂种大鼠的眼球震颤搏动次数和持续时间相同,且显著高于Wistar无特定病原体大鼠(P小于0.01)。眼球震颤频率无差异。结果表明,动物束缚系统对眼球震颤的定量特征,如持续时间和搏动次数,产生了显著影响。本文描述了一种轻柔束缚大鼠的系统。

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