Palma-Álvarez Raul Felipe, Ros-Cucurull Elena, Ramos-Quiroga Josep Antoni, Roncero Carlos, Grau-López Lara
Palma-Álvarez, MD, Ros-Cucurull, MD, PhD, Ramos-Quiroga, MD, PhD, Psychiatry Service, CIBERSAM, Vall Hebron University Hospital, Barcelona, Spain and Department of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, Spain. Roncero, MD, PhD, Psychiatry Service. University of Salamanca Health Care Complex, Institute of Biomedicine. University of Salamanca. Spain. Grau-López, MD, PhD, Psychiatry Service, CIBERSAM, Vall Hebron University Hospital, Barcelona, Spain and Department of Psychiatry and Forensic Medicine, Autonomous University of Barcelona, Barcelona, Spain.
Psychopharmacol Bull. 2019 Feb 15;49(1):92-97.
Cocaine-induced psychotic disorder (CIPD) is one of the most serious consequences of cocaine use. Despite the high frequency of CIPD, specific treatment for CIPD has been scarcely researched. Although supportive measures are the first approach, antipsychotic use is often necessary due to clinical severity and CIPD consequences. We report a 38-years-old man with substance use disorders in methadone maintenance treatment who relapsed on cocaine use and presented CIPD that was satisfactorily treated with asenapine. It is important further research on CIPD management, especially on asenapine and other second-generation antipsychotics du to its possible role in its treatment.
可卡因所致精神障碍（CIPD）是使用可卡因最严重的后果之一。尽管CIPD发病率很高，但针对CIPD的特异性治疗研究甚少。虽然支持性措施是首要方法，但由于临床严重性及CIPD后果，使用抗精神病药物常常是必要的。我们报告1例38岁正在接受美沙酮维持治疗的物质使用障碍男性，其可卡因使用复发并出现CIPD，使用阿立哌唑治疗效果良好。进一步研究CIPD的管理很重要，尤其是阿立哌唑及其他第二代抗精神病药物在其治疗中的可能作用。
