Yang Qiongwei, Guo Xiaoyun, Liu Dengtang
First-episode Schizophrenia and Early Psychosis Program, Division of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Minkang Hospital of Ningxia Civil Affairs Department, Ningxia, China.
Shanghai Arch Psychiatry. 2018 Jun 25;30(3):204-206. doi: 10.11919/j.issn.1002-0829.217168.
Hypokalemia can cause abnormalities in multiple systems. Long term use of antipsychotic medications can lead to electrolyte imbalance, including hypokalemia. We report a 49-year-old female patient with schizophrenia who developed hypokalemia after oral quetiapine and risperidone treatments. Her blood potassium became normal after she switched to another antipsychotic drug (amisulpride). In addition, we discuss the potential mechanism of antipsychotic drugs leading to hypokalemia and clinical cautions.
低钾血症可导致多系统异常。长期使用抗精神病药物可导致电解质失衡，包括低钾血症。我们报告一名49岁的精神分裂症女性患者，在口服喹硫平和利培酮治疗后出现低钾血症。在换用另一种抗精神病药物（氨磺必利）后，她的血钾恢复正常。此外，我们还讨论了抗精神病药物导致低钾血症的潜在机制及临床注意事项。
