Candelier J J, Couillin P, Eydoux P, Boué A
C R Acad Sci III. 1986;302(8):303-8.
The production of monoclonal antibodies against human embryonic renal cells allowed to display on the adult human kidney some antigens typical of certain structures or tissues: the proximal convoluted tubule for EG 9-11 and EG 19-6 monoclonal antibodies, the glomerular basement membrane for EG 14-1, the urothelium for EE 24-6, the connective tissue for EK 8-1 and EK 17-1 and probably the capsular and tubular basement membranes for EK 8-1. Simultaneously, we could follow the spatial and temporal repartition of the antigens during the renal development. One of them (EI 16-1) seemed to disappear in the adult and might correspond to a foetal type-antigen.
针对人胚胎肾细胞产生的单克隆抗体，使得某些特定结构或组织的典型抗原在成人肾脏上得以展现：对于EG 9-11和EG 19-6单克隆抗体而言是近端曲管，对于EG 14-1是肾小球基底膜，对于EE 24-6是尿路上皮，对于EK 8-1和EK 17-1是结缔组织，对于EK 8-1可能是包膜和肾小管基底膜。同时，我们能够追踪抗原在肾脏发育过程中的时空分布。其中一种抗原（EI 16-1）在成人中似乎消失了，可能对应一种胎儿型抗原。
