2019 年 WSES 外科患者（）感染管理指南更新。
2019 update of the WSES guidelines for management of () infection in surgical patients.
机构信息
Department of Surgery, Macerata Hospital, Via Santa Lucia 2, 62100 Macerata, Italy.
2Infectious Diseases Department, Trieste University Hospital, Trieste, Italy.
出版信息
World J Emerg Surg. 2019 Feb 28;14:8. doi: 10.1186/s13017-019-0228-3. eCollection 2019.
Abstract
In the last three decades, infection (CDI) has increased in incidence and severity in many countries worldwide. The increase in CDI incidence has been particularly apparent among surgical patients. Therefore, prevention of CDI and optimization of management in the surgical patient are paramount. An international multidisciplinary panel of experts from the World Society of Emergency Surgery (WSES) updated its guidelines for management of CDI in surgical patients according to the most recent available literature. The update includes recent changes introduced in the management of this infection.
摘要
在过去的三十年中，感染（CDI）在世界范围内许多国家的发病率和严重程度都有所增加。CDI 发病率的增加在手术患者中尤为明显。因此，预防 CDI 并优化手术患者的管理至关重要。世界急诊外科学会（WSES）的一个国际多学科专家小组根据最新的可用文献更新了其外科患者 CDI 管理指南。更新内容包括对这种感染管理的最新介绍。
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2
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