Al Kasab Sami, Almallouhi Eyad, Harvey Jillian, Turner Nancy, Debenham Ellen, Caudill Juanita, Holmstedt Christine A, Switzer Jeffrey A
Department of Neurology (SAK), University of Iowa; Department of Neurology (EA, NT, ED, CAH), Medical University of South Carolina, Charleston; Department of Healthcare Leadership and Management (JH), College of Health Professions, Medical University of South Carolina, Charleston; and Department of Neurology (JC, JAS), Augusta University.
Neurol Clin Pract. 2019 Feb;9(1):41-47. doi: 10.1212/CPJ.0000000000000570.
Inter-hospital transfer is important in the treatment of acute stroke. We sought to assess door in to door out (DIDO) time at spoke sites, and transportation time between spoke sites and thrombectomy-capable stroke center (TSC) in 2 large, rural telestroke networks.
Records of patients treated with tissue plasminogen activator through 2 telestroke networks between March 2017 and December 2017 were reviewed. Mann-Whitney test was used to compare median times, and a generalized linear regression model was used to predict the total time of care controlling for transportation distance.
Eighty-five patients were included with median NIH stroke scale on presentation of 13 (interquartile range [IQR] 7-17), median door to needle time 49 minutes (IQR 40-62), and median DIDO 111 minutes (IQR 92-157). Eighteen patients (21%) underwent computed tomography angiography (CTA) at spoke prior to transportation. Median DIDO was 169 minutes for patients who received CTA before transfer, compared with 107 minutes for patients who did not ( = 0.0004). Median door-to-groin time at TSC was 68 minutes for the CTA group and 85 minutes in the non-CTA group ( = 0.832). Controlling for distance, the predicted time of care from spoke door in time to groin puncture at TSC (sDTG) is 93.68 minutes longer for patients who receive CTA prior to transport ( = 0.034).
In the included telestroke networks, the sDTG time is longer when CTA is conducted at spoke site prior to transportation to TSC. New strategies are urgently needed to decrease sDTG when CTA is done prior to transfer to TSC.
医院间转运在急性卒中治疗中至关重要。我们试图评估两个大型农村远程卒中网络中分支站点的门到门(DIDO)时间,以及分支站点与具备血栓切除术能力的卒中中心(TSC)之间的转运时间。
回顾了2017年3月至2017年12月期间通过两个远程卒中网络接受组织纤溶酶原激活剂治疗的患者记录。采用曼-惠特尼检验比较中位数时间,并使用广义线性回归模型预测控制转运距离后的总护理时间。
纳入85例患者,就诊时美国国立卫生研究院卒中量表中位数为13(四分位间距[IQR]7 - 17),门到针时间中位数为49分钟(IQR 40 - 62),DIDO中位数为111分钟(IQR 92 - 157)。18例患者(21%)在转运前在分支站点接受了计算机断层扫描血管造影(CTA)。转运前接受CTA的患者DIDO中位数为169分钟,未接受CTA的患者为107分钟(P = 0.0004)。CTA组在TSC的门到股动脉穿刺时间中位数为68分钟,非CTA组为85分钟(P = 0.832)。控制距离后,转运前接受CTA的患者从分支站点门进时间到TSC股动脉穿刺的预测护理时间(sDTG)长93.68分钟(P = 0.034)。
在所纳入的远程卒中网络中,在转运至TSC之前在分支站点进行CTA时,sDTG时间更长。当在转运至TSC之前进行CTA时,迫切需要新的策略来缩短sDTG。