Department of Medicine, Division of Endocrinology and metalolism, Universidade Federal de São Paulo, End: Street Leandro Duprat, 365, São Paulo, 04025-010, Brazil.
Department of Surgery, Division of Surgical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil.
Eat Weight Disord. 2020 Jun;25(3):637-642. doi: 10.1007/s40519-019-00663-2. Epub 2019 Mar 11.
Some studies have shown an increase in alcohol use disorders (AUD) after Roux-en-Y gastric bypass surgery (RYGB), but its relationship with binge eating disorder (BED) has not been fully explored. The purpose of this study was to determine the prevalence of AUD and BED after RYGB and also to evaluate if BED is predictive of late postoperative occurrence of AUD or BED.
Patients (n = 46) submitted to RYGB, in a tertiary outpatient weight management service at a Federal University of Sao Paulo, Brazil, were tested for BED and AUD using the Questionnaire on Eating and Weight Patterns-Revised (QEWP-R) and AUDIT, respectively. BED was tested before surgery, while both disorders were evaluated with a follow-up period of 12 ± 1.6 years after RYGB.
No patients reported AUD before RYBP. After a mean period of 12 years from surgery, ten patients (21.7%) were diagnosed with AUD. Before surgery, BED was present in 24 patients (52.2%) and it was detected in seven out of these 24 patients (29.2%) after RYGB. Thirteen new cases of BED (28.2%) were detected after surgery; total of 20 patients (43.5%) with BED. No association was found between pre- and postsurgery BED (p = 0.148). After RYGB, four out of 24 patients (16.6%) with presurgery BED developed AUD, and no association was found between presurgery BED and postsurgery AUD (p = 0.384). Seven out of ten patients (70%) with AUD after RYGB also developed BED, but no statistical significance was found between these two disorders (p = 0.061).
The presence of BED before RYGB did not predict AUD and BED after RYGB. Nevertheless, factors involved in a possible association between BED and AUD after surgery remain to be determined.
Level III, cohort study.
一些研究表明，在 Roux-en-Y 胃旁路手术后（RYGB），酒精使用障碍（AUD）的发生率增加，但与暴食障碍（BED）的关系尚未得到充分探讨。本研究旨在确定 RYGB 后 AUD 和 BED 的患病率，并评估 BED 是否预测术后晚期 AUD 或 BED 的发生。
在巴西圣保罗联邦大学的一家三级门诊体重管理服务机构中，对 46 名接受 RYGB 的患者使用饮食和体重模式问卷修订版（QEWP-R）和 AUDIT 分别测试 BED 和 AUD。BED 在手术前进行测试，而两种疾病都在 RYGB 后 12 ± 1.6 年的随访期间进行评估。
没有患者在 RYBP 前报告 AUD。手术后平均 12 年，10 名患者（21.7%）被诊断为 AUD。手术前，24 名患者（52.2%）存在 BED，其中 7 名（29.2%）在 RYGB 后被检出。手术后又发现了 13 例新的 BED（28.2%）；共 20 例（43.5%）患者患有 BED。术前和术后 BED 之间没有相关性（p=0.148）。在 RYGB 后，24 名术前 BED 患者中有 4 名（16.6%）出现 AUD，术前 BED 和术后 AUD 之间没有相关性（p=0.384）。在 RYGB 后，10 名 AUD 患者中有 7 名（70%）也出现了 BED，但两者之间没有统计学意义（p=0.061）。
RYGB 前 BED 的存在并不能预测 RYGB 后 AUD 和 BED。然而，手术后 BED 和 AUD 之间可能存在关联的因素仍有待确定。
三级，队列研究。
