Vanderbilt University School of Medicine, 2201, West End Ave., Nashville, TN, USA.
Instituto de Virologia 'Dr. J.M. Vanella', Facultad de Ciencias Medicas, CONICET, Universidad Nacional de Cordoba, Av. Enfermera Gordillo s/n, Cordoba, Argentina.
Int Health. 2019 Jul 1;11(4):314-315. doi: 10.1093/inthealth/ihy101.
Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradication worldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usually constrained by testing costs.
We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141 individuals.
The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotype or viral load (in samples with such information, 90%).
The HCV test validated in this study can allow for HCV screening in areas of need when properly used.
直接作用抗病毒药物治疗丙型肝炎已使全球范围内能够讨论丙型肝炎的清除。要实现这一目标，需要在资源有限的地区进行大规模筛查，这通常受到检测成本的限制。
我们在三个不同的大陆上对 141 名个体进行了一种低成本、快速诊断检测（RDT）的验证。
无论基因型或病毒载量如何（在有此类信息的样本中为 90%），HCV RDT 在不同样本中均显示出 100%的特异性和敏感性。
当正确使用时，本研究中验证的 HCV 检测可在有需要的地区进行 HCV 筛查。
